Research Scientist (Sequencing Biochemistry & Enzymology)

Job Location
Little Chesterford
United Kingdom
Industry leading package


Company equity, annual bonus scheme, 10% pension, private healthcare and more!

Job Description


Research Scientist (Sequencing Biochemistry & Enzymology)

Permanent / Full-Time; Cambridgeshire, UK

Industry leading remuneration package which includes company equity, annual bonus scheme, 10% pension, share purchase scheme, gym membership and more!


Want to be a part of the winning team?
Illumina win Genomics England Project - first of its kind in the world
Illumina develop the world's 1st platform capable of sequencing a human genome for under $1000
Illumina outstrip their competitors for speed, accuracy and throughput
Illumina’s NGS platform combines the power of microfluidics, fluorescence detection, SBS chemistry and powerful informatics to create a robust and high through-put sample to answer solution.  Underpinning this technology are the biochemical reactions that facilitate our patented sequencing by synthesis (SBS) chemistry.  As part of the Consumables Development group, we are looking for a Research Scientist with a strong background in molecular biology.  The ideal person will be someone who has experience developing and troubleshooting protocols (ideally NGS applications), and has a solid understanding of the protein and chemical aspects that can affect the success of an assay.  We want someone more interested in the protocol than the result, who asks the question “why do we put that into the reaction?”


You will be joining a team that is responsible for optimizing the fundamental aspects of SBS chemistry, including buffers, polymerases and template interactions.  If you want the chance to take Illumina NGS to the next level, this is the role for you.


  • Perform lab-bench based experiments to improve the performance of Illumina sequencing platforms.
  • Contributing to the ongoing development of Illumina's DNA sequencing systems.
  • Perform analysis of complex datasets and provide interpretations that drive towards results.
  • Work in close collaboration with other members of the Sequencing Biochemistry team.
  • Provide regular updates on progress.


This role represents a rare opportunity to join Illumina’s R&D headquarters in Cambridge and work as part of team researching the key technologies that underpin Illumina’s platforms.  If you are looking for an opportunity to join a well-resourced function that works at the forefront of DNA sequencing technology, then this is well worth considering. 


Preferred background

  • PhD in Genetics, Molecular Biology or Biochemistry
  • Hands on experience in NGS platforms, in either academic or industrial setting.
  • Must possess a strong background in molecular biology, and experience protein biochemistry (purification, enzyme kinetics and biophysics) is highly desirable.
  • Sound understanding of the latest genomics technologies, methodologies, and practices across the industry.
  • Strong data analysis skills, ability to interpret and draw conclusions from vast amounts of data.
  • Experience in NGS applications for genomic analysis preferred.
  • Must be detail oriented and highly motivated to be a part of a fast paced, multidisciplinary and dynamic environment.
  • Solid communication and writing skills required.


How to Apply
About Our Organization

Headquartered in San Diego, California, Illumina (NASDAQ: ILMN), is a leading developer, manufacturer, and marketer of next generation life science tools and integrated systems for large-scale analysis of genetic variation and biological function. These systems are enabling studies that were not even imaginable just a few years ago, and moving us closer to the realization of personalized medicine. With the innovative advances in our sequencing technologies, we are rapidly impacting the clinical market in areas such as reproductive health and oncology. The expanding Illumina oncology portfolio of next- generation sequencing NGS and microarray technologies is revolutionizing cancer genomics research. Our customers include a broad range of academic, government, pharmaceutical, biotechnology, and other leading institutions around the globe.

NIH's Michael Lauer looks at the number of grants, their amount, and funding success rates at the agency for last year.

At Nature, Johns Hopkins' Gundula Bosch describes her graduate program that aims to get doctoral students thinking about the big picture.

Patricia Fara writes about childcare funding, and women in science and science history at NPR.

National Institute of Environmental Health Sciences researchers have visualized the career paths of former postdocs.