Research Scientist II

Broad Institute
Job Location
Cambridge, MA
Job Description

The Broad Institute of MIT and Harvard is the world’s leading biomedical research institute dedicated to the bold mission of using the full power of genomics to transform the understanding and treatment of disease. The Broad Institute seeks to describe all of the molecular components of life and their connections; discover the molecular basis of major human diseases; develop effective new approaches to diagnostics and therapeutics; and disseminate discoveries, tools, methods, and data openly to the entire scientific community.

Founded in 2004 by Eric Lander and philanthropists Eli and Edythe L. Broad, the Broad Institute includes faculty, professional staff, and students from throughout the MIT and Harvard biomedical research communities and beyond, with collaborations spanning more than a hundred private and public institutions in more than 40 countries worldwide.

The Heiman lab aims to understand how neuronal identity is established and maintained, and how the molecular identity of a neuron determines its susceptibility to disease. Lab members use biochemical, genetic, and molecular biological tools, including mouse models of neurodegenerative diseases and a novel methodology termed Translating Ribosome Affinity Purification (TRAP) that allows molecular profiling of individual types of neurons from within the mammalian brain.

Characteristic duties:
- Makes substantial contributions to determining goals, objectives, and research methods to be used
- Identifies and resolves complex technical and methodological problems
- Makes detailed observations, analyzes/interprets experimental data, and presents results
- Leads efforts to analyze current project operations and makes recommendations for process improvements
- Initiates new project concepts and recommends new research directions
- Independently performs most assignments with instructions as to the general results expected
- Makes significant contributions to scientific papers, reports and presentations
- Strong organizational, time management, and project management skills required
- Superior research skills
- Must be able to work independently as well as part of a team in a fast-paced, highly collaborative environment
- Must possess a high level of initiative and the ability to work with little supervision
- Superior written and verbal communication skills, with the ability to clearly communicate scientific objectives and project results

- PhD with 2+ years of related job experience
- Mastery of rodent stereotaxic surgery strongly required
- Experience with rodent behavioral assays required
- Mastery with molecular biology techniques required
- Primary cell culture experience preferred but not required
- Excellent communication skills and the ability to interact professionally with all levels
- Excellent organization and time management skills
- Must be able to use sound judgment to handle a variety of tasks and to shift priorities

EOE/Minorities/Females/Protected Veterans/Disabilities

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