Research Scientist I

Organization
Takara Bio USA (Formerly Clontech Laboratories, Inc)
Job Location
1290 Terra Bella Ave
Mountain View, CA 94043
Job Description

Position Summary

Takara Bio USA is looking for a highly skilled, creative, and self-motivated individual with experience in chemical biology, chemistry and biochemistry to join our talented team of researchers. The successful candidate will have a passion for turning ideas into practical tools and be responsible for the development of the kits for protein and antibody purification, manipulation and characterization utilizing Clontech brand novel CapturemTM high-capacity membrane based technology.

Primary Duties & Responsibilities

  • Plans and conducts well thought-out experiments at the bench on one or more projects relating to develop of novel methodologies for fast protein and antibody purification, manipulation, and controlled enzymology
  • Works with under guidance from Product Managers and senior scientists to ensure projects are developed according to specifications and set deadline
  • Provides clear reports, summarizing data and interpretation
  • Learns and adheres to quality system protocols
  • Identifies potential new products for development based on assessment of customer demand, market trends, and competitor analysis with help from Product Managers and more senior researchers in the group
  • Drafts SOPs, user manuals and other related technical documents, with assistance from more senior R&D members
  • Serves as resource to R&D and other departments within the organization, including Product Management, Planning, QC, and Product Transfer
  • May attend scientific meetings to present posters and represent Research and Development
  • May support Technical Support representatives on technical matters
  • Additional duties as assigned
Requirements
  • Ph.D. and post-doctoral experience in Biochemistry, Chemistry, Chemical Biology or related discipline, with a focus on protein science
  • Advanced knowledge and experience in synthetic organic chemistry, protein chemistry, protein engineering, refolding, purification and characterization using various methodologies such as SEC, IEX, Affinity, HIC, LC-MS, CE, HPLC/FPLC, etc
  • In depth experience of bioconjugation of proteins with fluorescent and other detection probes
  • Familiarity with enzyme/antibody characterization, quality control, functional and stability assays
  • Familiarity with biochemical and biophysical characterization techniques to develop reproducible medium/large scale protein preps suitable for LC-MS, X-ray crystallography and various drug discovery related biochemical assays
  • Hands-on experience with various molecular biology methods such as gene manipulation, cloning and protein expression
  • Additional experience with technologies characterizing protein-small molecule or protein-protein interactions would be a plus
  • Effective analytical and problem solving skills
  • Collaborative personality with strong interpersonal skills

*  Excellent oral and written communication skills

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