Research Histotechnologist I

Organization
Fred Hutchinson Cancer Research Center & Seattle Cancer Care Alliance
Job Location
Seattle, WA
Job Description

Cures Start Here.
Fred Hutchinson Cancer Research Center (Fred Hutch), home of three Nobel laureates, is an independent, nonprofit research institution dedicated to the development and advancement of biomedical research to eliminate cancer and other potentially fatal diseases. Recognized internationally for its pioneering work in bone-marrow transplantation, Fred Hutch's five scientific divisions collaborate to form a unique environment for conducting basic and applied science. The Fred Hutch, in collaboration with its clinical and research partners, the University of Washington and Seattle Children's, is the only National Cancer Institute-designated comprehensive cancer center in the Pacific Northwest.

Careers Start Here.
A highly qualified and motivated research histotechnologist is sought to join a lab in the Clinical Research Division of the Center. The laboratory investigates the molecular and cellular drivers of pancreatic ductal adenocarcinoma (PDA) or, more commonly, pancreas cancer, in order to transform the standard of care for patients with this disease.

The lab has engineered highly faithful murine models of preinvasive, invasive and metastatic PDA through targeted endogenous expression of mutations in a key oncogene and select tumor suppressor genes. These models serve as the primary platforms for our Murine Clinical Trials Program designed to accelerate the translation of early detection, diagnostic and treatment strategies to the clinic. Ideas developed through this effort are now in clinical trials in patients. This represents an excellent opportunity for a highly motivated individual with a passion for science to work and learn in a dynamic scientific environment while addressing important problems relevant for the successful treatment of pancreas cancer.

The histotechnologist will establish and optimize histochemical, immunohistochemical and immunofluorescence procedures for a team of pancreas cancer researchers. S/he will be involved in all steps of these procedures including fixation and embedding of tissues, sectioning, staining, analyses and presentation of findings and will be responsible for the overall histopathology operations of the laboratory. The histotechnologist will also maintain the state-of-the-art equipment used within histology, including processors, microtomes and autostainers.

A bachelor's degree in a biological science and a minimum of two years of experience as a histology technician is required. Previous experience with TMA construction, antibody "cocktailing" and IHC/IF multiplexing is advantageous. Strong troubleshooting skills and the ability to multi-task with precise attention to detail is especially critical. To be successful in this position, the applicant must be capable of taking initiative and working independently.

Certification by a nationally recognized agency, such as the American Society of Clinical Pathology, is required.

 

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