Research Associate

Baylor College of Medicine Human Genome Sequencing Center
Job Location
One Baylor Plaza
Houston, TX 77030
Job Description

The Baylor College of Medicine Human Genome Sequencing Center (BCM-HGSC) is seeking to recruit a Research Associate to work in the Library Group. 

Job Summary:

The Library Construction group is responsible for preparation of samples for sequencing across multiple NextGen sequencing platforms. The position would principally involve DNA and RNA QC, construction of DNA and RNA libraries for Next-Generation sequencing pipelines (Illumina, Ion Torrent and PacBio), qPCR, sequence capture as well as work with Illumina genotyping arrays. The candidate should have strong molecular biology background and be able to work independently and within a team. Candidate may be required to lead a team/sub-team in the Library group to support the production pipeline and work under the direction of the Group Manager. The candidate should be able to work well in a team environment.


  • Independently perform laboratory research projects, R &D experiments and production tasks.
  • Test early access protocols and write evaluation reports.
  • Troubleshoot experiments.
  • Collect, compile, evaluate and analyze data.
  • Design and conduct research experiments.
  • Draft SOPs and summarize information in an appropriate format.
  • Document experiment results and report to team lead.
  • Oversee the maintenance of lab equipment and environment.
  • May assign activities to less experienced research staff.
  • Perform other related job duties as assigned.

Essential Background Required:

  • Required: Ph.D. OR Master's degree with 1-2 years experience in a biological sciences
  • Qualified candidates should have strong molecular biology experience in one or more of the following molecular biology areas is essential: DNA and RNA manipulations such as purification and qualification, PCR and qPCR, and restriction enzyme digestion and good organizational skills.
  • Experience in Next Generation sequencing library construction, Microarrays.
  • Proficiency in MS Word and MS Excel is necessary.
  • Qualified candidates should be good at multi-tasking, problem-solving, and have strong communication skills.

Desired/Preferred Background:

  • Preferred is prior supervisory experience and working in a high- throughput setting in the genomics or microarray laboratories.
  • Illumina arrays experience with automated liquid handling platform, use of LIMS, experience working in a CLIA laboratory is desirable.


How to Apply

Submit your Resume and CV to:
Lita Abreu
Human Resources Manager
Human Genome Sequencing Center
Baylor College of Medicine
1 Baylor Plaza
Mail stop: BCM226
Houston, TX 77030-3411


Phone: 713-798-3936

About Our Organization

The Baylor College of Medicine Human Genome Sequencing Center (HGSC) was founded in 1996 under the leadership of Dr. Richard Gibbs and is a world leader in genomics. The fundamental interests of the HGSC are in advancing biology and genetics by improved genome technologies. As one of the three large-scale sequencing centers funded by the National Institutes of Health, the HGSC provides a unique opportunity to work on the cutting-edge of genomic science in a state of the art institution. Today, the HGSC employs ~ 200 staff, and it occupies more than 36,000 square feet on the 14th, 15th, and 16th floors of the Margaret M. and Albert B. Alkek Building. The HGSC is located on the southwest edge of downtown Houston, the fourth largest city in the U.S., in the Texas Medical Center, the world's largest medical complex. The major activity of the HGSC is high-throughput DNA sequence generation and the accompanying analysis. The HGSC is also involved in developing the next generation of DNA sequencing and bioinformatics technologies that will allow greater scientific advances in the future.

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