Research Associate

Organization
10x Genomics
Job Location
San Francisco Bay Area, CA 94566
Job Description

10x Genomics is seeking a highly-motivated individual to come join its chemistry team. This person will assist in performing advanced research that combines new approaches in chemistry, microfluidics, biochemistry, molecular biology and bioinstrumentation. They will meticulously execute and troubleshoot experiments that include: sample preparation, next-generation sequencing library construction, cell culture and handling, PCR, microfluidic device characterization, polymer synthesis and other routine molecular biology/analytical techniques. The Research Associate will also analyze data and assist in the preparation and delivery of presentations and reports along with maintaining detailed experimental documentation.

Key Responsibilities

  • Productive execution of well thought out experiments, accurate recording of results along with in-depth analysis and reporting of these results.
  • Assist in design and implementation of robust chemistries which enable novel biochemical reactions in a microfluidic environment.
  • Develop a deep understanding of the interplay between chemistry, biology and microfluidics for root cause analysis and process optimization.
  • Establish orthogonal analytical assays for product and component characterization.
  • Conduct stability, guard band, workflow variability and system verification testing.
Requirements
  • Minimum of a BS in chemistry, biochemistry, chemical engineering or bioengineering.
  • 2+ years relevant experience developing successful products in life science applications, such a DNA sequencing, PCR or other nucleic acid based technologies
  • Ability to develop, validate and transfer processes to technical transfer group.
  • Methods development capability for a broad range of standard techniques as well as ability to develop novel methods based on the requirements of the product.
  • Experienced in the analysis and interpretation of complex data sets.
  • Desire to be part of a rapidly evolving organization, with a compelling technology, and taking products and processes to the next level.

Desired Skills and Background

  • Experience with droplet microfluidics including: microparticle synthesis, biomolecule encapsulation dynamics, and droplet unit operations.
  • Demonstrated ability to create and implement complex multi-step assay schemes.
  • Experience with microscopy, quantitative fluorescence imaging and high-speed imaging.
  • Knowledge in programming (Python, R, Excel macros etc.)
  • Understanding and experience with next-generation sequencing workflows and data analysis.
How to Apply
About Our Organization

Changing the definition of sequencing isn’t just our tagline – it’s a commitment to game-changing advances in the field of genomics. Fueled by equal parts scientific vision and determined passion, we are delivering unprecedented innovation to short-read sequencing technologies and transforming how genomic information is accessed. You will feel the 10x difference the moment you enter our offices and labs. There’s a dynamic energy here, and we’re looking for the best of the best to be a part of it.

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