Research Assistant

Organization
The Jackson Laboratory for Genomic Medicine
Job Location
Ten Discovery Drive
Farmington, CT 06030
Job Description

The Hinson laboratory at The Jackson Laboratory for Genomic Medicine in Farmington, CT is seeking a talented Research Assistant III, experienced in stem cell and molecular biology. The focus of the Hinson laboratory is to understand the molecular and genetic basis of inherited cardiac disorders. We employ diverse approaches but we are particularly focused on the development of novel, biomimetic tissue models of cardiomyopathy using disease-specific induced pluripotent stem cells (iPScs). The Hinson lab is ideally seeking a highly-motivated individual who has prior experience with human iPSc handling and experimentation.

Responsibilities

  • Applies knowledge of the scientific principles, methods and processes (technical and/or theoretical) to conduct a systematic and objective inquiry including experimental design, data collection and analysis; operate instruments and equipment; and use of related information technology.
  • Performs tests, procedures and experiments applying specialized skills, knowledge and equipment; modifies and refines techniques and procedures to meet research objectives; manages multiple, concurrent projects or a multi-faceted project.  Trouble shoots new protocols.
  • Monitors and maintains sample databases, collects research data to assess accuracy, validity, and integrity.
  • Coordinates and manages facilities, equipment, supplies and related resources; monitors environmental risks and quality control; understands and complies with safety standards to maintain a safe environment.
  • Clearly and concisely conveys information verbally and in written form; effectively presents ideas to individuals or groups to ensure that they understand the information and message.  Presents research results and summaries; adheres to reporting requirements of research project(s).
Requirements
  • Knowledge of biological sciences as would normally be acquired through Bachelor’s degree in biological sciences and with at least 2 years of directly related laboratory experience.  Other means of acquiring that knowledge and experience may be evaluated on a case-by-case basis.
  • Recommended skills and experiences include stem cell tissue culture especially human iPScs, in vitro differentiation, DNA and RNA extraction and analysis, next-generation DNA and RNA sequencing (NGS), molecular cloning, immunohistochemistry, Western blotting and flow cytometry. The Hinson lab is also experienced in genome engineering of stem cells with CRISPR/CAS9 and TALE nucleases, in vitro cardiac differentiation, flow cytometry, NGS assays especially RNAseq and single cell RNAseq, and basic microfabrication. A candidate with prior experience in microfabrication and photolithography would also be highly desired, but not required. The candidate should have basic familiarity with biostatistics.
  • The candidate should be hardworking, able to work independently, have strong written and communication skills, able to work in a team environment, acquire new skills rapidly, and have versatility in a laboratory setting.
  • Strong organizational and communication skills.
  • Strong analytical and computer skills, proficiency with Microsoft Access, Excel, Word, and Outlook.
  • Effective problem solving and interpersonal skills.
How to Apply

Please apply online to requisition #5302 at www.jax.org/careers.

About Our Organization

 

The Jackson Laboratory (www.jax.org) is an independent, nonprofit biomedical research institution and National Cancer Institute-designated Cancer Center with more than 1,700 employees. Headquartered in Bar Harbor, Maine, it has a facility in Sacramento, Calif., and a new genomic medicine institute in Farmington, Conn. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

Founded in 1929, the Laboratory applies its eight decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease.  It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and empowers the global biomedical community by providing critical data, tools and services. 

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