Production Development Scientist

Twist Bioscience
Job Location
San Francisco, CA
Job Description

 As a Scientist in the Production Development group, you will use your skills in molecular biology to interface between R&D and Operations to establish new processes at scale for gene synthesis products in manufacturing. You will work with Automation engineers to implement new processes. You will collaborate with the QC team to identify key control points and qualify all new methods. You will report to the Manager, Tech Transfer and will work cross-functionally with other teams to develop, verify and validate all new processes in this lab based position.

Key Responsibilities:

  • Work closely with R&D to gain thorough understanding of new product designs
  • Collaborate with R&D to transform process knowledge into high throughput production methods for gene synthesis
  • Independently design experimental plans, perform studies, analyze large data sets, and report study results and recommendations both verbally and in written formats
  • Define product specifications, processing parameters and operational boundaries
  • Work with software engineers to develop workflow support and LIMS features
  • Collaborate with Automation team to develop and optimize methods at scale
  • Collaborate with QC team to evaluate new processes and methods at scale
  • Become fluent with end-to-end gene synthesis workflow
  • Write technical documents including work instructions, SOP’s and training documents for manufacturing operators
  • Train manufacturing operators
  • Write verification and validation test plans
  • Work cross-functionally to execute V&V plans and evaluate results

Minimum Qualifications:

  • D. in Biochemistry, Molecular Biology, Microbiology, Bioengineering, or related field
  • 3+ years industrial experience in biotechnology product development and/or technical transfer
  • Experience with Tableau, Spotfire, or JMP


Required Qualifications:

  • Proven ability to launch products in a biotechnology or life sciences company
  • Ability to work in a fast paced, team environment
  • Experience with automation platforms such as Hamilton/Biomek/Tecan or Echo is a plus
  • Background in molecular biology techniques including PCR, DNA purification (column and bead based), DNA quantification (absorbance and fluorescence), DNA assembly (Gibson, Golden Gate, Restriction Enzyme), and molecular cloning.
How to Apply

To become part of this growing start up, please go to and apply!

About Our Organization

At Twist Bioscience, our expertise is accelerating science and innovation by leveraging the power of scale. We have developed a proprietary semiconductor-based synthetic DNA manufacturing process featuring a 10,000-well high throughput silicon platform capable of producing synthetic biology tools, including genes, oligonucleotide pools and variant libraries. By synthesizing DNA on silicon instead of on traditional 96-well plastic plates, our platform overcomes the current inefficiencies of synthetic DNA production, and enables cost-effective, rapid, high-quality and high throughput synthetic gene production, which in turn, expedites the design, build, test cycle to enable personalized medicines, pharmaceuticals, sustainable chemical production, improved agriculture production, diagnostics, biodetection and data storage. For more information, please visit Twist Bioscience is on Twitter. Sign up to follow our Twitter feed @TwistBioscience at

Twist Bioscience is an equal opportunity and an e-verify employer.

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