The Sheltzer Lab at Cold Spring Harbor is seeking candidates for an NIH-funded postdoctoral position studying the systems biology of cancer progression.
The Sheltzer Lab is developing an integrated platform to understand the genomic differences between fatal and non-fatal human tumors. Using the latest GEO and TCGA data, we are identifying genes and genomic features that correlate with survival times across cancer types. We are then following up these in silico discoveries with in vitro and in vivo work to characterize the mechanisms underlying these associations and to find new therapeutic targets that can block cancer lethality. Through the use of CRISPR, RNAi, and drug screening, we are working to enhance our understanding of the biology that underlies metastasis and death from cancer.