Postdoctoral Researcher in Computational Biology

The Jackson Laboratory for Genomic Medicine
Job Location
Farmington, CT 06032
Job Description

A postdoctoral research position in computational biology is available in Principal Investigator Sheng Li’s lab at the Jackson Laboratory for Genomic Medicine.

The goal of the Li Lab is to contribute to the development of novel therapies that address cancer evolution. Our research focuses primarily on (1) understanding the epigenome dynamics during cancer evolution over time and under therapy; and (2) the mechanisms and translational implications of cancer cells population heterogeneity and plasticity.

We are looking for applicants who are excited to work in the creative and dynamic environment ingrained in JAX’s collegial, collaborative, interdisciplinary, and diverse research culture.


The postdoctoral researcher is expected to develop new analytical methods for cancer epigenome/transcriptome data integration, and to analyze bulk and single-cell sequencing data sets from clinical studies.


  • PhD in a statistics, biostatistics, computer science, physics, computational biology, bioinformatics, or a related field with knowledge of statistics

  • A strong computational background (proficiency in at least one programming language required)

  • Excellent communication skills and fully fluent spoken and written English

  • A passion for solving cutting edge research problems of computational biology

The following optional qualifications are considered advantageous:

  • Knowledge of (and/or work experience with) machine learning methods

  • Experience with large-scale data analysis using software pipelines in an HPC environment

  • Experience in software development

  • Research experience in next-generation sequencing data analysis and utilization of public available bioinformatics resources


How to Apply

Apply via our careers page to posting #5856 [click here for direct link]; with your application, please upload a single pdf file containing your CV, full publication list, and contact information for three references.

EEO: The Jackson Laboratory is an equal opportunity employer. Qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

About Our Organization

The Jackson Laboratory is a world-renowned research and educational institution with programs in computational biology, genomics, bioinformatics, genome technology, cancer, aging, stem cell, neurobiology, immunology, and microbiome. The Laboratory is recognized internationally for its excellence in research and educational activities, unparalleled genomic resources, and outstanding research support services. It has been voted one of the country’s top 15 “Best Places to Work in Academia” in a poll conducted by The Scientist magazine.

The Jackson Laboratory for Genomic Medicine (JAX-GM) is part of an exciting $1.1 billion venture between The Jackson Laboratory and the state of Connecticut. JAX-GM comprises 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities. The new institute is located in Farmington, Connecticut, within the uniquely interdisciplinary and multicultural Hartford metropolitan area. Farmington is within a two-hour drive of both New York City and Boston.

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