Postdoctoral Researcher in Comparative Functional Genomics

Organization
UConn Health (Cotney Lab)
Job Location
400 Farmington Ave
R1158
Farmington, CT 06030-6403
Salary
Commensurate with experience.
Job Description

Postdoctoral positions in comparative functional genomics for both experienced molecular biologists and computational biologists are available in the Cotney Lab within the Department of Genetics and Genome Sciences and the Institute for Systems Genomics at UConn Health . Our laboratory is applying functional genomics techniques (ChIP-Seq, RNA-Seq, ChIA-PET, Hi-C, etc) to identify novel gene regulatory elements in early mammalian embryonic development. We seek to understand the genetic basis of the evolution of the human form and developmental disorders by integrating multiple types of functional genomics data from a variety of tissues and species.

Requirements

We seek molecular biologists with a variety of experimental experience including:

  • General tissue culture techniques, including culturing of human and mouse cell lines, primary cells, embryonic stem cells and iPS.
  • Transient and stable cell transfection, virus­-based infection.
  • RNAi­-based knock­down and vector­ mediated ectopic expression, marker­based positive clone selection.
  • Cell-­based assays to evaluate viability.
  • Protein analysis by western blotting, enzymatic assays.
  • DNA/RNA sequencing
  • Chromatin immunoprecipitation
  • Genome editing (CRISPR)
  • Enhancer screens and activity measurement

We seek computational biologists with experience related to functional genomics:

  • Scripting languages such as Python, Perl, or Awk
  • Statistical packages such as R or Matlab
  • Next generation sequencing data such as ChIP-Seq, RNA-Seq, etc.
  • Statistical genetics including GWAS and 1000 Genomes data sets.
  • Comparative genomics such as multi-species alignments and conservation analysis.
  • Visualization of genomic data including Circos, IGV, UCSC Genome browser, etc.
  • 3D Modeling or experience with computer game development

The ideal candidate would have a mixture of both experimental and computational skills.

How to Apply

Applicants should send a CV and a list of three references by email to cotney@uchc.edu or via the form available on the Cotney Lab website.

About Our Organization

UConn Health is a vibrant, integrated academic medical center that is entering an era of unprecedented growth in all three areas of its mission: academics, research, and clinical care.

UConn Health is at the center of Bioscience Connecticut, a bold plan introduced by Connecticut Governor Dannel P. Malloy and approved by the Connecticut General Assembly in 2011. The plan will strengthen Connecticut’s position as a national and global leader for bioscience innovation and improve access to quality health care for Connecticut citizens for generations to come.

Based in Farmington, Connecticut – a popular suburb of the state’s capitol of Hartford – UConn Health is home to the School of Medicine, School of Dental Medicine, John Dempsey Hospital, UConn Medical Group, UConn Health Partners, University Dentists and a thriving research enterprise.

With approximately 5,000 employees, UConn Health is a major economic driver in the region, generating nearly $1 billion annually in gross state product. It is closely linked with the University of Connecticut’s main campus in Storrs through multiple, cross-campus academic projects.

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