Postdoctoral Positions in Prostate Metastasis Evolution – Trotman Lab
The laboratory of Lloyd Trotman is seeking outstanding postdoc candidates for research on the evolution of metastasis using molecular biology and genome sequencing techniques.
We are particularly interested in candidates with a track record of developing original solutions to tackle fundamental questions in biology. Our team has recently developed a unique mouse model system to recapitulate human prostate metastasis and its therapy, called RapidCaP (Cancer Discovery, 2014, PMID: 24444712). Now, we are studying the molecular and genetic events that give rise to metastasis and therapy resistance. Projects center around defining a roadmap to metastasis through the study of cancer evolution that includes single cell genome sequencing. Furthermore, we aim to understand how this roadmap can be perturbed through innovative therapeutic interventions. A second area of great interest involves design of new genome editing tools to functionally validate candidate cancer genes in the RapidCaP