A postdoctoral position is currently available, in the laboratory of Dr. David L. Spector, for a highly motivated outstanding individual to study Long Non-Coding RNAs (lncRNAs) in Breast Cancer Progression. lncRNAs are an exciting class of thousands of RNAs among which very few have thus far been functionally characterized. We recently performed an RNA-seq screen in mouse mammary tumors and organoids vs normal mammary glands and identified differentially expressed lncRNAs. The proposed studies will build upon these findings and use innovative methods, including patient-derived tumor organoids, to interrogate the functional role of specific lncRNAs in mammary tumor initiation, progression, and metastasis, as well a their potential as therapeutic targets. Experience in molecular biology, mouse models, breast cancer, and genomic analysis is a plus.
Cold Spring Harbor Laboratory provides a highly dynamic and interactive environment for scientific research. In addition, our Meetings and Courses program provides an opportunity for interacting with a broad range of researchers and exposure to timely advances in many areas of scientific research.
Interested individuals within one year of receiving or having received their Ph.D. should send their CV, a statement of research accomplishments and interest in this position, and the names of 3 references to Dr. David L. Spector ([email protected]). Please visit our web site at http://spectorlab.labsites.cshl.edu.