Position description: We are seeking a highly-motivated Postdoctoral candidate committed to research in cancer genomics. The overarching goal of the Bell lab is to identify pathogenic driver genes that underlie the development of the most clinically aggressive forms of human endometrial cancer. Our research entails next generation sequencing of clinical samples at the NIH Intramural Sequencing Center, in silico mining of large publically available genomic datasets, and functional annotation of mutations in candidate driver genes. The successful applicant will use bioinformatics approaches to analyze in-house and publically available next-generation sequence data to identify candidate cancer genes, with the possibility of utilizing molecular, biochemical, and cellular approaches to functionally discriminate driver mutations from passenger mutations in selected genes-of-interest. Access to extensive core facilities including cores in bioinformatics, microarrays, copy number analysis, flow cytometry, cytogenetics, and a transgenic mouse core, offers the trainee wide latitude in the design and pursuit of their research questions. Extensive career development opportunities are available through the NHGRI Intramural Training Office and the NIH Office of Intramural Training and Education.