Postdoctoral Fellowship in Clinical Bioinformatics

CSIRO (Commonwealth Scientific and Industrial Research Organisation)
Job Location
AU $78K to AU $88K plus up to 15.4% superannuation

Work with innovative researchers in Australia’s premier science and technology organisation which is engaged in world-class scientific research projects. We offer excellent career development, professional support, and opportunities to collaborate with World-leading MND researchers.

CSIRO’s North Ryde Site offers a family friendly work environment with child-care facilities on site and the option to salary-sacrifice child-care fees.  CSIRO is an equal opportunity employer and proudly supports a number of diversity initiatives relating to Women in Science, LGBTI inclusion and indigenous engagement.

Job Description

• Be mentored by Australia’s finest scientific researchers at CSIRO

• Contribute to cutting-edge research with global impact

• Collaborate with our research partners at the Macquarie Motor Neurone Disease Research Centre

The position:

This is a great opportunity for you to undertake innovative research in clinical bioinformatics and statistical genetics with Australia’s premier researchers at CSIRO.  As a Postdoctoral Fellow with CSIRO Health and Biosecurity, you will have a unique opportunity to translate your research into practice with impact on both Australian and international e-Health programmes.

The successful candidate for this role will be highly motivated, enthusiastic and ready to make a significant contribution to the genetics and genomics aspects of a recently funded NHMRCteam grant.  The Postdoctoral Fellow will work closely with researchers from CSIRO’s Transformational Bioinformatics Team as well as with research colleagues at the Macquarie Motor Neurone Disease Research Centre.  The research aims to elucidate the genetic component of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS), also known as motor neurone disease (MND).

Make a hands-on contribution to solving the research challenges in processing raw data from large-cohort whole genome sequencing, DNA methylation and gene expression datasets.  Develop methodologies using traditional high-performance compute parallelization strategies and novel BigData approaches (e.g. Spark) to clarify molecular function or support the genomic engineering of animal models. Liaise with other international contributors to Project MinE to coordinate analysis pipelines.

Sydney has a vibrant and cosmopolitan atmosphere and is one of the world’s most loved cities. With exquisite dining, unique cultural activities, spectacular sightseeing and a number of idyllic beaches within easy reach, Sydney is a green, global and connected city.  The North Ryde Site is well located and has a family friendly work environment. Child-care facilities are on site and CSIRO offers the option of salary-sacrificing child-care fees. The role provides excellent career development via our structured postdoctoral program, as well as professional support including ‘Women in Science’ activities and opportunities to collaborate with World-leading MND researchers.

We are looking to fill this role and get you settled in as soon as possible, so click on the “Position Details” link at CSIRO Careers to see specific duties and selection criteria.  Apply today!

Location:     North Ryde (Sydney) New South Wales

Salary:        AU $78K to AU $88K plus up to 15.4% superannuation

Tenure:       3 year term

Ref No.:       24162

Owing to terms of the fellowship, candidates must not have more than 3 years of relevant Postdoctoral experience.

Applications close Sunday 14 August, 2016 (11:59pm AEST)



  1. Education/Qualifications:  A doctorate (or will shortly satisfy the requirements of a PhD) in a relevant discipline area, such as bioinformatics, computer science, information technology, or engineering.

    Please note: To be eligible for this role you must have no more than 3 years of relevant postdoctoral experience.


  3. Communication:  High level written and oral communication skills with the ability to represent the research team effectively internally and externally, including at national and international conferences.

  4. Publications:  Publications in academic environments such as scientific journals/conference presentation (please list impact in your CV, e.g. number of citations, journal impact factor, conference acceptance rate).

  5. Behaviours:  A history of professional and respectful behaviours and attitudes in a collaborative environment.

Essential Criteria:

  1. Demonstrated extensive experience in NGS data analysis, large cohort human variant analysis and a deep understanding of the underlying genetic concepts (e.g. genotypes, heritability, LD, complex genetic traits).

  2. Demonstrated experience with Hadoop-based compute engines (e.g. SPARK) as well as high-performance compute environments (e.g. PBS, SLURM).

  3. Evidence of advanced programming skills and software design in multiple languages relevant for bioinformatics (e.g. Python, C++, Java, Scala, BASH, R, or equivalent).

  4. Proven ability to work effectively as part of a bioinformatics team to develop and complete research tasks, as well as the motivation and discipline to carry out autonomous research.

  5. A demonstrated ability to interact with external/internal collaborators and stakeholders.

    Desirable Criteria:

  1. Experience with data analysis and interpretation of genomic sequence variants for clinical utility (e.g. NATA accreditation).

  2. Experience with large international collaborations and evidence of impact in them.

  3. Good understanding of emerging trends in medical informatics (e.g. FHIR), personal genomics,  and/or genome editing (e.g. GeneDrive).

How to Apply

Please follow the direct link to the ad on CSIRO Careers ( ) and be sure to click on the "Position Details" link before applying.  Your application should include one document incorporating the latest version of your CV plus a covering letter outlining your motivations for applying and your suitability for the role (uploaded under “Resume/Cover Letter”).

About Our Organization

At CSIRO we invent the future. We do this by using science and technology to solve real issues. Our solutions make a difference to industry, people and the planet. As Australia’s national science agency we’ve been pushing the edge of what’s possible for almost 90 years. Today we have thousands of talented people working across Australia and internationally. Our people work closely with industry and communities to leave a lasting legacy. Collectively, our innovation and excellence places us in the top ten applied research agencies in the world. We Collaborate to Innovate.

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