Postdoctoral Fellowship in Bioinformatics and Evolutionary Genomics

Organization
National Human Genome Research Institute, National Institutes of Health
Job Location
Bethesda, MD
Job Description

A postdoctoral training position is currently available in the Computational and Statistical Genomics Branch (CSGB) of the National Human Genome Research Institute (NHGRI). The position is located in the laboratory of Andy Baxevanis, Ph.D., whose research group uses comparative genomics approaches to better-understand the molecular innovations that drove the surge of diversity in early animal evolution. The overarching theme of Dr. Baxevanis’ research program is focused on how non-traditional animal models convey critical insights into human disease research.

With this translational context in mind, Dr. Baxevanis’ group is currently leading an international effort to sequence two cnidarian species: Hydractinia echinata and Hydractinia symbiolongicarpus. The regenerative abilities of these colonial hydrozoans make them excellent models for the study of key questions related to pluripotency, allorecognition, and stem cell biology, work that will be significantly advanced by the availability of high-quality whole-genome sequencing data from these organisms. In addition, and in collaboration with colleagues at the Whitney Marine Laboratory of the University of Florida, the group has now begun sequencing Chaetopterus, a polychaete worm that exhibits exceptional regenerative abilities; this organism also shows particular promise for advancing our understanding of early developmental processes and bioluminescence. The successful applicant will have the opportunity to develop and apply bioinformatics approaches to these and other large-scale genomic data sets, focusing on the evolution of specific protein families, with an emphasis on examining their putative roles in disease causation.

Requirements

Candidates should have or be close to obtaining a Ph.D. or equivalent degree in bioinformatics, computational biology, computer science, molecular biology, or a closely related field. Candidates with a background in evolutionary biology are particularly encouraged to apply. Programming skills and experience in the application of computational methods to genomic data are highly desirable. Applicants must possess good communication skills and be fluent in both spoken and written English. The ability to learn how to use new software and quickly become expert in its use, critical thinking, problem-solving abilities, and the ability to work semi-independently are required.

About Our Organization

The NIH Intramural Research Program is on the Bethesda, Maryland campus and offers a wide array of training opportunities for scientists early in their careers. The funding for this position is stable and offers the trainee wide latitude in the design and pursuit of their research project. The successful candidate will have access to NHGRI’s established and robust bioinformatics infrastructure, as well as resources made available through NIH’s Center for Information Technology (CIT) and the National Center for Biotechnology Information (NCBI).

For more information on CSGB and NHGRI’s Intramural Research Program, please see http://genome.gov/DIR/.

 DHHS and NIH are Equal Opportunity Employers and encourage applications from women and minorities.

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