Postdoctoral positions are available for motivated and creative individuals in the laboratory of Adam Williams Ph.D. at the Jackson Laboratory for Genomic Medicine.
Asthma is an allergic disease of the airways that has reached epidemic proportions. Although it is widely accepted that asthma is caused by a dysregulated immune response we do not understand why or how this happens; this lack of understanding is a major stumbling block in the generation of new therapies for the prevention and treatment of asthma. Through the use of both human and mouse systems my lab will explore the potential role of the non-coding RNAs in the development of asthma and will seek to identify novel targets for therapeutic intervention.
The long-term goals of the laboratory are:
1. Identify non-coding RNAs important in regulating immune function in health and disease.
2. Define mechanisms of non-coding RNA function.
3. Identify targets for therapeutic intervention.
To accomplish these goals, we will use state-of-the-art high-throughput sequencing methodologies and CRISPR/Cas9 genome editing technologies.