One postdoc position is available in the laboratory of Dr. Yue Wan at the Genome Institute of Singapore. We are broadly interested in using biochemical and genomics approaches to study how RNA structures impact RNA function in the cell. Website: ywanlab.com
How an RNA folds into its secondary and tertiary structure is crucial for its function. While traditionally RNA structures are studied in a low throughput manner, recent advances in high throughput sequencing has enabled the simultaneous determination of thousands of RNA secondary structures in solution. This greatly expands our ability to study RNA structural organization in the cell and how this organization impacts gene regulation. Being one of the first people to develop high throughput RNA structure probing, we are interested in utilizing and extending existing high throughput approaches to understand how RNAs function in microbial and mammalian systems(Kertesz et al., 2010; Wan et al., 2011; Wan et al., 2012; Wan et al., 2014).
We are seeking a highly motivated and independent postdoctoral fellow with a proven academic track record and interest in interdisciplinary research. The successful candidate should have a Ph.D in molecular and cellular biology, biochemistry, genetics or related field and have rich experience in RNA biology, cell biology and genomics. The postdoc will have opportunities to interact closely with bioinformaticians and other research groups in the Genome Institute of Singapore.