Postdoctoral Fellow (Microbial Program) | GenomeWeb

Postdoctoral Fellow (Microbial Program)

Lawrence Berkeley National Laboratory
Job Location
Walnut Creek, CA
Job Description

Postdoctoral Fellow (Microbial Program) - 80135
Organization: GN-Genomics

The Department of Energy Joint Genome Institute - DOE JGI (a division of the Lawrence Berkeley National Laboratory) has an exciting opportunity available for a postdoctoral fellow. Under general supervision, this position will work on single-cell projects and be responsible for the establishment of methodologies that will enable the selective isolation, whole genome amplification and sequencing of single environmental microbial cells in a high throughput manner. Research will focus on cells involved in the degradation of plant biomass, such as cellulose, xylan, xyloglucan. You will perform phylogenetic and functional diversity studies and comparative sequence analysis. This role will report to the Microbial Genomics Program Lead.

• Create, design, and execute experiments that will enable the selective isolation and shotgun sequencing of microbial cells of interest, mostly based on desired activity.
• Develop fluorescent labeling methods for targeted single-cell isolations by micromanipulation and/or FACS.
• Work with isolates involved in cellulose degradation to benchmark and test new methods.
• Analyze genomic shotgun metagenomic sequence data, as well as single-cell data: build phylogenetic trees, analyze annotated genomes, and perform comparative genome analyzes and focus on plant biomass degradation pathways.
• May keep an accurate and detailed laboratory notebook.
• May summarize experiment results in reports and papers submitted for publication and present analysis results at scientific meetings.
• May attend and present data at group meetings.


• PhD in Biology, Molecular Biology, Microbiology, Biochemistry, Genetics, or related field
• High degree of experience with fluorescent-labeled substrates and fluorescent-activated cell sorting
• Knowledge of Molecular Biology Techniques such as: PCR, qPCR, Cloning, Multiple Displacement Amplification
• Knowledge in microbial ecology, physiology, biochemistry, biogeochemistry, molecular biology
• Familiar with plant biomass degradation processes in microorganisms
• Familiar with basic sequence analysis tools, ie. ARB, BLAST, CLUSTALW, PFAM
• Experience using PC, Mac and/or UNIX operating systems
• Ability to apply technology skills in troubleshooting problems
• Excellent interpersonal skills for working in a diverse team environment and strong written and verbal communication skills to present findings at group meetings and conferences and publish results
• Excellent organizational and record keeping skills to record experiment results and analyze data
• Ability to interact with a variety of technical and scientific personnel including Research Associates, Scientists and Software Engineers
• Preferred - Experience in annotation and analysis of genomes, pathways and families of genes and proteins
• Preferred - Experience with next generation sequencing platforms (Illumina, PacBio)

Notes: This is a 2-year postdoctoral appointment with the possibility of renewal dependent on performance, continuing availability of funds and ongoing operational needs. Work will be performed at the DOE Joint Genome Institute (JGI), located in Walnut Creek, CA. This position requires completion of a background check.

About Us
Rapid technological advances in genomics have transformed modern biology. From its inception, the Department of Energy Joint Genome Institute has been at the forefront of large-scale sequence-based science. Learn more about JGI happenings at and

Berkeley Lab addresses the world’s most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab’s scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy’s Office of Science. Read about the excellent benefits at Berkeley Lab.

Berkeley Lab understands the postdoctoral experience in a research environment is unique. We are committed to the growth and development of early career researchers in pursuit of becoming next generation scientists and engineers. Read about the excellent postdoctoral benefits at Berkeley Lab.

Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability, age or protected veteran status.

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