Postdoctoral Fellow in Immunology/Epigenetics/Infection Biology
Short Summary: The Bergthaler laboratory at the CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences in Vienna offers a position for a Postdoctoral Fellow who aims to employ cutting-edge tools to investigate the molecular interface between antiviral immunity, epigenetics and inflammation.
The Project: The successful applicant will contribute to our ongoing efforts to unravel novel molecular mechanisms of genome-wide changes during the antiviral immune responses. Following on a recent study of our lab (Schliehe C. et al. Nat Immunol 2014), the aim of this project is to study the function of chromatin-modifying proteins in homeostasis and disease. An integrated approach of RNAseq, ChIPseq, and proteomics with specific biochemical assays and well-defined genetic systems of cell culture and animal disease models is expected to yield novel insights into the molecular regulation of inflammation and pathogen clearance. Knowledge of handling and integration of large data, as well as own project ideas on the topic are welcomed and should be detailed within the application.
The Candidate: You have received your PhD, MD or DVM no later than 4 years ago and have a strong publication track record with several first-author papers in internationally recognized peer-reviewed journals. You have obtained extensive experimental training in molecular cell biology and biochemistry and bring a solid pathophysiological understanding of inflammatory and infectious diseases. Expertise with animal models and computational biology are welcomed additional assets.
We look for a highly motivated colleague who is enthusiastic to work on a fundamental biological question. You should be a critical scientist and a creative mind to think the unthinkable. Being a team player and strong interdisciplinary communication skills are required.
The Lab: Our aim is to unravel novel molecular mechanisms of inflammatory and infectious diseases such as superinfections and chronic viral infections. We employ an integrative approach of infection models and complementary state-of-the-art tools of immunology, genetics, pathology and systems biology. The lab offers a highly dynamic and competitive environment with access to latest technologies within a thriving institute.
The principal investigator received training in premier laboratories in Japan, Switzerland and the US and leads a research group consisting of 8 members from 7 countries. The lab maintains collaborations with leading scientists and clinicians of the Medical University of Vienna and other national and international institutions. Scientific and social interactions are supported by lab meetings, journal clubs, seminars with renowned guest speakers and by annual lab retreats. The lab is funded by intramural funds from the Austrian Academy of Sciences as well as by external grants (Austrian Science Fund (FWF), European Research Council (ERC)). Bergthaler lab websites: http://www.bergthaler1.at and http://alturl.com/crjkm .
References: Schliehe C. et al. Nature Immunology 2015 (PMID: 25419628), Bhattacharya A et al. Immunity 2015 (PMID: 26588782), Litvak V. et al. Nature 2012 (PMID: 22982991)
The Institute: CeMM is a biomedical flagship institute in the heart of Europe, Vienna. We are committed to highest scientific standards and provide an international environment representing approximately 40 nationalities. The working language is English. CeMM has been ranked by The Scientist as one of the Best Places to Work Academia worldwide (link: http://goo.gl/51VMO). In the past 3 years CeMM groups published numerous groundbreaking studies about inflammation, cancer and infection in prestigious journals such as Science, Cell, Nature, New England Journal of Medicine, Nature Immunology, Immunity etc. CeMM is located within the medical campus of Vienna and operates several technology platforms (chemical biological screening, proteomics, metabolomics, next-generation sequencing) as well as extensive bioinformatics infrastructure.
Funding and Starting Date: Initial funding is available, but candidates are encouraged to seek for post-doctoral fellowships. Salary scale according to the Austrian Science Fund (FWF). Starting date as soon as possible.
Contact: Interested candidates are encouraged to send their application (including a cover letter, a CV and names and contact details of at least 2 referees) using the reference code #PD-AB-21 to https://cemm.jobbase.io/job/q2eehivr. .
This call will remain open until the position is filled.