Neurodevelopmental disorders are a common group of developmental disabilities affecting individuals of all ages. Understanding the causes and biological mechanisms underlying these disorders is crucial to improve the ability to diagnose and treat individuals.
The Icahn School of Medicine at Mount Sinai is looking for a post-doctoral researcher to assess the role of noncoding RNAs in gene regulatory networks underlying neurodevelopmental disorders. The position involves integrating noncoding and coding RNA expression data with prior genetic knowledge, as well as quantifying noncoding RNA isoforms, co-expression and network-based analyses and modeling. The candidate will use the latest next-generation sequencing technologies to analyze transcriptomes and identify long full-length noncoding RNA isoform variants.
We seek a highly motivated postdoctoral candidate with strong computational and analytical skills and an interest in applying computational and systems biology approaches. The ideal candidate will have a Ph.D. in genomics, bioinformatics with a strong background in RNA biology and excellent quantitative skills. The selected applicant will work within a multidisciplinary team and be part of a recently funded NIMH PsychENCODE project. This position requires extensive experience with UNIX, Python, C/C++ and statistical environments such as R, and familiarity with large-scale GWAS and RNA-Seq data.
Specific qualifications include:
- Experience in the following areas:
- Mapping RNAs using short and long-read RNA sequencing data
- Annotation and reconstruction of transcript isoforms
- Co-expression and network-based/modeling
- Familiarity with large-scale GWAS
- Programming (python, C/C++, or Java)
- Statistical analysis (using R or Matlab)
- Ability to complete tasks efficiently and independently
- Strong work ethic and attention to detail
- Excellent verbal and written communication skills
- Ability to work in a collaborative setting
The Icahn School of Medicine at Mount Sinai is an equal opportunity/affirmative action employer. We recognize the power and importance of a diverse employee population and strongly encourage applicants with various experiences and backgrounds.