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Postdoctoral Fellow, Gastrointestinal Cancers

Organization
Canada's Michael Smith Genome Sciences Centre at BC Cancer
Job Location
100-570 West 7th Ave.
Vancouver, BC V5Z 4S6
Canada
Job Description

About us
Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer is an international leader in genomics, proteomics and bioinformatics for precision medicine. By developing and deploying genome sequencing, computational and analytical technology, we are creating novel strategies to prevent and diagnose cancers and other diseases, uncovering new therapeutic targets, and helping the world realize the social and economic benefits of genome science

Learn more about how the GSC is Bringing Genomics to Life.

Why work at the GSC
As the first genome centre to be established within a cancer clinic, our story began by thinking outside of the box. From being the first in the world to sequence the SARS coronavirus during the 2003 global outbreak to publishing the first study demonstrating the use of whole-genome sequencing to influence personalized cancer treatment planning in 2010, our passion for pushing scientific frontiers continues to this day.

Our technology platforms enable the transformative science being done at the GSC, but it is our world-class team of scientists and innovators that make it happen. By joining the GSC you will become part of a diverse and dedicated group of biologists, bioinformaticians, computer scientists, computational biologists, biochemists, engineers, and clinicians. We look for people who share our core values—science, timeliness, and respect—to join us in our mission to provide genomics, bioinformatics, and proteomics technology and expertise for the benefit of human health and society.

We believe that diversity and inclusivity are essential for the advancement of human knowledge and science. We welcome all applicants and provide all employees with equal opportunity for advancement, regardless of race, colour, ancestry, place of origin, political belief, religion, marital status, family status, physical or mental disability, sex, sexual orientation, gender identity or expression, age, conviction of a criminal or summary conviction offence unrelated to their employment.

All qualified candidates are encouraged to apply; however, Canadian citizens and permanent residents will be given priority.

*Due to COVID-19 restrictions, the position may require working remotely.  This restriction would be re-evaluated upon re-contracting*

Role Summary

A Post-doctoral position is available immediately for a highly motivated recent PhD or MD/PhD graduate to join a dynamic translational research group, headed by Dr. Isabella Tai, Associate Professor in the Division of Gastroenterology, University of British Columbia and Senior Scientist at the Genome Sciences Centre, BCCA.

Current projects in the laboratory revolve around improving our understanding of the mechanisms involved in the development of chemotherapy resistance and metastasis in gastrointestinal cancers (colorectal, gastric, liver and biliary cancers). The goal is to develop either novel therapeutic targets for GI cancer treatment or novel screening tools for diagnosis.  We continue to use the latest genomics (including single cell sequencing), proteomics and bioinformatic approaches to identify potential targets or markers for this purpose.   The following link provides an overview of all current projects: (https://www.bcgsc.ca/people/isabella-tai)

Eligibility 

Interested individuals with a recent PhD or MD/PhD and strong publication records and excellent academic credentials are encouraged to apply.  Experience in molecular biology, cell biology, tissue culture and animal tumor models, is preferable.  Experience in bioinformatics is an asset.

UBC hires on the basis of merit and is committed to employment equity.  We encourage all qualified persons to apply.  However, Canadians and permanent residents of Canada will be given priority. 

Duration

3 years (possibility of extension).

Contact

Please submit a cover letter, curriculum vitae, and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience, long-term career goals and an indication of the desired length of postdoctoral position. 

Please send your resume with cover letter to [email protected].

How to Apply

Please submit a cover letter, curriculum vitae, and the names of three referees willing to provide letters of reference. The cover letter should include a brief description of your previous research experience, long-term career goals and an indication of the desired length of postdoctoral position. 

Please send your resume with cover letter to [email protected].

About Our Organization

Canada's Michael Smith Genome Sciences Centre (GSC) at BC Cancer has since worked with local, national and international partners on the Human Genome Project, on many cancer projects and on reference genomes for a diversity of species. In 2003, we were the first in the world to sequence the genome of the SARS coronavirus. By 2006, we received one of the world's first "next generation" DNA sequencing machines (the Solexa/Illumina) and became famous for high throughput and large scale sequencing; to date, we have sequenced nearly 3 quadrillion (3,000,000,000,000,000) nucleotide bases—equivalent to nearly one million human genomes.

We have trained thousands of highly qualified personnel in genomics, computational biology and bionformatics, published many thousands of peer-reviewed papers in some of the world's most influential scientific journals, attracting nearly 100,000 citations. We have been part of hundreds of diverse research projects in the health and life sciences and have contributed to many thousands of national and international research collaborations. Our scientists have been leaders on projects awarded more than $1 billion from more than 100 different funders around the world. In 2019, 11 GSC researchers were among the most highly cited in the world.

We are now bringing genome sequencing, bioinformatic techniques and expertise to whole populations of cancer patients, helping to prevent, diagnosis and treat many different cancers in entirely new ways and identifying risks for hereditary cancers. In the process, we are learning about the genomic underpinnings of other diseases, revealing causes of rare genetic disorders and uncovering unique therapeutic targets. We are making discoveries that are shaping the world's fundamental understanding of life, health and disease. Learn more. 

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