A postdoctoral position is available at the Risques Lab, Department of Pathology, University of Washington (Seattle, WA, USA) to work in the advanced development of two novel DNA Next Generation Sequencing (NGS) technologies with multiple applications in cancer research. The first technology is called PolyG-MIP and enables the subclonal detection of indels in polyguanine tracts that are captured, molecularly tagged, and sequenced with Molecular Inversion Probes (MIPs). The main applications of PolyG-MIP are analysis of intratumor heterogeneity, characterization of cancer evolution, and early detection of cancer. The second technology is called Duplex Sequencing and it reduces the error rate of NGS from 1 in 103 to 1 in 107 . We are using this unprecedented sensitivity for early detection of ovarian cancer in peritoneal fluid and Pap smear DNA. Depending on experience, the postdoc will work on advanced development and applications of PolyG-MIP or Duplex Sequencing. More info about the Risques Lab can be found at www.depts.washington.edu/risques/. This is a full-time position and is initially available for two years, but may be extended.