Postdoctoral Fellow- Cancer genetics

University of Washington
Job Location
Seattle, WA
Commensurate or better than NIH standards depending on experience
Job Description

A postdoctoral position is available at the Risques Lab, Department of Pathology, University of Washington (Seattle, WA, USA) to work in the advanced development of two novel DNA Next Generation Sequencing (NGS) technologies with multiple applications in cancer research. The first technology is called PolyG-MIP and enables the subclonal detection of indels in polyguanine tracts that are captured, molecularly tagged, and sequenced with Molecular Inversion Probes (MIPs). The main applications of PolyG-MIP are analysis of intratumor heterogeneity, characterization of cancer evolution, and early detection of cancer. The second technology is called Duplex Sequencing and it reduces the error rate of NGS from 1 in 103 to 1 in 107 . We are using this unprecedented sensitivity for early detection of ovarian cancer in peritoneal fluid and Pap smear DNA.  Depending on experience, the postdoc will work on advanced development and applications of PolyG-MIP or Duplex Sequencing. More info about the Risques Lab can be found at This is a full-time position and is initially available for two years, but may be extended.


PhD in molecular biology, genome sciences, biochemistry, or related. This position requires strong background in molecular biology, experience in NGS library preparation and data analysis, ability to work independently, and outstanding communication skills and interpersonal skills. Prior experience in cancer genetics and advanced computing knowledge is desirable. A track record of excellent first author publication is essential.

How to Apply

Applications should be sent by email to Rosana Risques ( Please write ‘postdoc application’ in subject line and attach a single PDF file that includes a cover letter, CV, names and contact information of 3 references, and up to 3 reprints of publications. Applications will be reviewed immediately with the position to be filled as soon as possible. Applications will be accepted until the position is filled.

About Our Organization

The University of Washington (UW) is a premier research institution that includes more than 270 specialized research centers and it is the home of 6 Nobel Prizes since 1989. The Risques Lab is in the Department of Pathology, which ranks annually among the top recipients of NIH funding for research grants among the departments of pathology in the country. UW Medicine Pathology brings together state-of-the-art technology, nationally and internationally recognized faculty, and a supportive and collaborative environment.  

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