An interdisciplinary team including expertise in pharmacy, genomics, epigenetics, metabolomics, and inflammatory response has recently been funded by NIH. A postdoctoral-level position is open to direct the bioinformatics analysis and integration of data. The selected postdoctoral candidate will join a dynamic, interdisciplinary team to investigate how natural chemical products regulate aberrant inflammatory processes and related signaling pathways via epigenetic modification during the suppression of inflammation and related diseases, including cancers.
A key position is available immediately to integrate genome-wide data for epigenetic patterns and changes in gene expression. Next generation sequencing approaches will include RNA-seq, ChIP-seq, and RRBS. The applicant will have the opportunity to work closely with members of each research group and draw upon the strengths of diverse experimental platforms, areas of expertise, and styles of mentorship.
The area of focus for this position will be the identification and characterization of novel inflammatory epigenetic and gene expression pathways linked to cell metabolism.
Candidates will perform bioinformatics and statistical analysis, visualization and data interpretation of data generated by the project. Candidates will use a variety of methods to identify genomic and metabolomic related signatures associated with metabolic activity from high dimensional biological data. Candidates will integrate data from external (e.g. NCBI GEO, UCSC Genome Browser, Ingenuity) and internal sources in analyses. Candidates will work independently with oversight from research faculty. Candidates will communicate Bioinformatics results to principal investigators and bench scientists. Candidates must have an excellent publication record and strong written and verbal communication skills.