Microbial Genomics Section, National Human Genome Research Institute
Our laboratory utilizes experimental and computational biology to explore human-associated microbiota (bacteria, fungi, virus) that contribute to health and disease. We utilize animal models of colonization, infection to explore hypotheses from human natural history clinical studies. We have two areas of focus, exploring both hospital outbreaks of multi-drug resistant organisms and the skin microbiome. See papers from the laboratory including Snitkin Science Translational Medicine 2012, Findley Nature 2013, Oh Genome Research 2013, Conlan Science Translational Medicine 2014, Oh Nature 2014.
Postdoctoral fellows are fully-integrated into basic-translational research with a range of collaborators in infectious disease, clinical microbiology, hospital epidemiology and dermatology. NHGRI has excellent training opportunities to interact with other laboratories and core facilities, including NIH sequencing center, bioinformatics, mouse transgenesis and knock-outs. As well, we are actively engaged in natural history patient studies at the research-based NIH Clinical Center.