A Postdoctoral position in computational biology/genomics is available in the Statistical Genomics and Systems Genetics group (http://www.ebi.ac.uk/research/stegle) at the European Bioinformatics Institute (EMBL-EBI) located on the Wellcome Trust Genome Campus near Cambridge in the UK.
The group is developing statistical data integration methods to tie together information about gene/disease associations from different sources to predict drug targets. The project will be carried out as part of the Centre for Therapeutic Target Validation (CTTV), a three-way collaboration between EMBL-EBI, the Wellcome Trust Sanger Institute (WTSI) and GlaxoSmithKline (http://www.targetvalidation.org/). This is a public-private initiative to generate evidence on the validity of therapeutic targets, and is committed to sharing its data openly with the scientific community.
The fellow will be in the Stegle group, and collaborate with the Saez-Rodriguez group and other research teams involved in the CTTV to develop new statistical methods for tying together multi-layered omics data to predict gene/disease associations. The primary goal is to derive new ways to fill-in information on gene/disease targets, for example using matrix factorization algorithms or related approaches. This project offers a unique opportunity to develop innovative statistical methods to fully exploit cutting edge datasets generated within the CTTV, thereby addressing a major question in human health.
EMBL-EBI is part of the European Molecular Biology Laboratory (EMBL); we are a world-leading bioinformatics centre providing biological data to the scientific community with expertise in data storage, analysis and representation. We provide a dynamic, international working environment and have close ties with both the University of Cambridge and the Wellcome Trust Sanger Institute. EMBL-EBI staff enjoy many benefits including excellent sports facilities, a free shuttle bus to Cambridge and other nearby centres, an active sports and social club and an attractive working environment set in 55 acres of parkland.