Autism Spectrum Disorder (ASD) is a lifelong neurodevelopmental disorder characterized by deficits in social communication and interaction, repetitive and restrictive behavior, extensive clinical and etiologic heterogeneity, and currently has a remarkably rising global prevalence rate. It is currently believed that ASD has an underlying genetic basis, ranging from effects of single genes to that of multiple genes, chromosomal regions and environmental factors, hallmarking the multifactorial and complex etiology. The research project aims to comprehensively identificaty the spectrum of genetic etiologic risk factors in ASD, to develop better diagnostic markers and apply early and effective intervention, utilizing large-scale, high-throughput genomic approaches.
To fulfill its mission, QBRI invites applications for a recent PhD holder to work within this exciting field
- To lead the post-computational analysis, including:
- Inheritance pattern analysis
- Validation of identified variants
- Investigation of variant pathophysiologic effects
- To develop different approaches to the molecular diagnostic testing of ASD
- To interface with researchers both within and outside the team
- To assist the bioinformaticians in directing their analyses
The successful candidate will be mentored and given the opportunity to develop his/her own projects in preparation for a future independent career.