Post-Doctoral Research Fellow, Microbiome and Vaccine Induced Immunity

Fred Hutchinson Cancer Research Center & Seattle Cancer Care Alliance
Job Location
Seattle, WA
Job Description

Cures Start Here .
At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutch's pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nation's first and largest cancer prevention research program, as well as the clinical coordinating center of the Women's Health Initiative and the international headquarters of the HIV Vaccine Trials Network.

Careers Start Here.
A new lab at the Vaccine and Infectious Disease Research Division is recruiting a postdoctoral fellow to work on a project investigating the role of the microbiome on vaccine-induced immunity. Our goal is to learn how the gut microbial and immune systems communicate to shape HIV vaccine immune responses. We are interested in how the microbiome shapes immune responses to HIV vaccines and contributes to vaccine response heterogeneity.

The incumbent will work with the team to conduct correlates analyses with clinical and mouse microbiome and immunogenicity data; we will unravel mechanisms of immunity by perturbation of the immune system and the microbiome - the immune system via multiple adjuvanted immunization regimens and the microbiome by gut microbial reconstitution in germ free mice; and we will conduct metabolomics case-control analyses from select human and mouse samples.

The candidate must be responsible, organized, and self-motivated, and able to efficiently manage time and experiments. In addition, the candidate must be familiar with aerobic and anaerobic cultures and/or murine models.

To be considered, candidates should have:
- A PhD in molecular biology, immunology, or a related field. Preference will be given to candidates with extensive experience in microbiology and/or immunology
- The candidate must show initiative, the willingness to take up new skills and responsibilities, and be a team player
- Willingness to work with human cells, murine models, and biohazardous/infectious agents (BSL2+) under carefully controlled conditions
- Ability to work both independently and as part of a laboratory team
- Excellent attention to details.

The successful candidate will be a highly motivated individual, with a willingness to take up new skills and responsibilities, as well as exceptional communication and organizational skills.

 To apply for this position, please CLICK HERE

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