Post-doctoral position in Computational Biology / Bioinformatics

Harvard Medical School & Massachusetts General Hospital
Job Location
Job Description

Post-doctoral position in Computational Biology, Bioinformatics, Systems Biology (MGH, Harvard Medical School)

Applications are invited for a post-doctoral position in Computational and integrative Systems biology in the laboratory of Dr. Aylwin Ng at Massachusetts General Hospital (MGH) and Harvard Medical School (

We are seeking creative and highly motivated applicants who have a strong interest in ‘Big Data’ analytics in the Biomedical sciences, and in pursuing Computational and Systems-level research into understanding microbial sensing, biological circuits, regulatory networks and pathways underlying microbial sensing, host immune responses and processes implicated in complex human inflammatory disorders, including Crohn’s disease, ulcerative colitis and Celiac disease. This position also provides opportunities to participate in exciting multi-disciplinary research programs investigating the interplay of host genetics and environmental factors (including pathogens and the gut microbiome) in influencing immune responses and disease outcomes.


Applicants should have a Ph.D., with a quantitative background in one or more of the following:
Computational biology, Computer science/Machine learning/Data-mining, Statistics, Mathematics or Physics.

Programming proficiency in Java or C, Python or Perl, and MATLAB or R is required. Additionally, experience in Next-Generation sequencing (NGS)/RNA-seq/ChIP-seq analysis, and/or genome-wide epigenetic profiling, as evidenced by scientific publications in peer-reviewed journals, would be a plus. Excellent written and verbal communication skills are essential.

How to Apply

Interested applicants should email your CV with contact information of three referees, and a cover letter outlining your research interests and career goals.  (Email: [email protected]

About Our Organization

The lab is situated in a vibrant and highly collaborative multi-disciplinary research environment within the Center for the Study of Inflammatory Bowel Disease (CSIBD) ( at the MGH which is currently ranked as one of the nation’s top hospitals. This lab benefits from close collaborations on both computational and experimental fronts within the CSIBD and state-of-the-art high-throughput screening and computational platforms at the Broad Institute of MIT & Harvard. Our lab utilizes integrative systems approaches involving computation and high-throughput experimentation (RNA interference (RNAi) and chemical biology screens, transcriptomics, proteomics, metabolomics, and data from genome-wide association studies (GWAS)).

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