Post Doctoral Fellow in Gen Epi/Functional Genomics

Organization
Cedars-Sinai Medical Center
Job Location
8700 Beverly Blvd
Los Angeles, CA 90048
Job Description

We are looking for a Postdoctoral Scientist to join the Center for Bioinformatics and Functional Genomics, to investigate the genetics underlying susceptibility to and development of ovarian cancer. The Genetic Epidemiology group within the Center studies the role of both germline and somatic genetic variation in ovarian cancer, with a specific focus on the role of non-coding variants and pathogenic coding mutations. Population based GWAS studies are coupled with whole genome sequencing studies in lymphocytes and tumor tissues to identify drivers of heritable cancer risk and tumor recurrence. We are searching for a talented post-doctoral fellow with training in genetic analysis methods that include: imputation and genome wide association analysis; eQTL analysis; analysis of large scale genomics datasets including RNA-seq, ChIP-seq and whole genome and exome sequencing; target gene resequencing in large populations of 1000s of subjects. 

The position requires a good appreciation of computational approaches to evaluate the contribution of genetic variation in the coding and non-coding genome to tumor initiation and development. The Center for Bioinformatics and Functional Genomics brings together teams specializing in bioinformatics and computational biology, functional analyses and next generation sequencing (3C/4C/HiC, ChIP-Seq) and genome editing to provide a complete pipeline for identifying the functional consequences of GWAS-identified risk loci and cancer susceptibility genes. The appointed postdoctoral scientist will work with a project scientist to perform genetic epidemiology studies (GWAS, sequencing studies). The post-holder should be able to work independently and within in a multiple disciplinary team comprising senior and junior post-doctoral scientists, research technicians, clinical fellows and graduate students.

The successful candidate will conduct research (both directed and independent) under the direction of Drs. Gayther and Jones, submit and publish papers and posters, and make oral presentations. This post-holder must be well organized and be able to demonstrate writing and presentation skills.

Requirements

Experience:
• The successful candidate should be able to demonstrate significant, original, and creative contributions to a research program and specific projects within that project.
• The candidate should have previous experience with the analysis of genetic (GWAS) and/or genomics datasets (array based, NGS or RNA-Seq). Knowledge of population genetics or cancer genetics. Demonstrated competency in a variety of data analysis techniques and protocols. 
• Good evidence of working independently and as part of a team.
• A publication track record in genetics and genomics analysis of coding and non-coding genetic variation

Essential job Duties and Responsibilities:
 Designs research studies and performs data analysis. 
 Will assist in collaborative projects where necessary if they can bring a unique expertise to a study.
 Will participate in and help organize weekly meetings.
 Will assist in the write-up data for publication.
 Will attend scientific meetings and present research findings.
 Will design and carry out studies independently and as part of the wider team
 Will Interpret, summarize and compiles results.
 Will write up data for publication as a senior author, and contribute to the preparation and publication of other research projects as a co-author 
 Will contribute to the writing and submission of grant proposals within the research team, and have the opportunity to write grant proposals for funding of research.

How to Apply

Please visit www.cedars-sinaimedicalcenter.apply2jobs.com and search for Requisition #24864 (or Post Doc Genetic Epidemiology) to apply online. 

Further information can be sought at michelle dot jones at csmc.edu

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