We are looking for a Postdoctoral Scientist to join the Center for Bioinformatics and Functional Genomics, to investigate the genetics underlying susceptibility to and development of ovarian cancer. The Genetic Epidemiology group within the Center studies the role of both germline and somatic genetic variation in ovarian cancer, with a specific focus on the role of non-coding variants and pathogenic coding mutations. Population based GWAS studies are coupled with whole genome sequencing studies in lymphocytes and tumor tissues to identify drivers of heritable cancer risk and tumor recurrence. We are searching for a talented post-doctoral fellow with training in genetic analysis methods that include: imputation and genome wide association analysis; eQTL analysis; analysis of large scale genomics datasets including RNA-seq, ChIP-seq and whole genome and exome sequencing; target gene resequencing in large populations of 1000s of subjects.
The position requires a good appreciation of computational approaches to evaluate the contribution of genetic variation in the coding and non-coding genome to tumor initiation and development. The Center for Bioinformatics and Functional Genomics brings together teams specializing in bioinformatics and computational biology, functional analyses and next generation sequencing (3C/4C/HiC, ChIP-Seq) and genome editing to provide a complete pipeline for identifying the functional consequences of GWAS-identified risk loci and cancer susceptibility genes. The appointed postdoctoral scientist will work with a project scientist to perform genetic epidemiology studies (GWAS, sequencing studies). The post-holder should be able to work independently and within in a multiple disciplinary team comprising senior and junior post-doctoral scientists, research technicians, clinical fellows and graduate students.
The successful candidate will conduct research (both directed and independent) under the direction of Drs. Gayther and Jones, submit and publish papers and posters, and make oral presentations. This post-holder must be well organized and be able to demonstrate writing and presentation skills.