The Levy Laboratory is the focal point of the Precision Vaccines Program at Boston Children’s Hospital/Harvard Medical School. The Program employs cutting edge technologies to understand age and sex-specific features of immune responses to inform development of vaccines tailored for optimal safety and immunogenicity towards distinct populations. We seek a skilled and motivated post-doctoral scientist with background in Bioinformatics to lead a project on characterizing global molecular (“OMIC”) signatures that predict immunogenicity of vaccines. Background in Immunology and Vaccinology is helpful but not required. Due to distinct immunity, most infection-induced death occurs at the extremes of life motivating development of improved vaccines that are safe and effective in the young and old. The project will employ recent knowledge in the areas of innate immune pathways (TLRs/inflammasome) and nanoparticle technology to identify adjuvants and enhance immune responses of those at the extremes of age in vitro and in vivo. Studies will employ in vitro modeling of human newborn, adult and elderly antigen-presenting cells, T and B lymphocytes as well as in vivo animal and human studies. Our laboratory is dynamic, international, supportive and productive. We are well funded by NIH, Gates Foundation, internal support as well as multiple sponsored research agreements. We offer excellent opportunities for publication, attendance at scientific meetings, and career advancement with graduates of the lab holding prominent positions in academia and industry. The candidate should have obtained their PhD within the last 1-3 years. Interested applicants should e-mail their CV and arrange to have 3 statements of reference e-mailed to: firstname.lastname@example.org.