Post Doctoral Associate (Bioinformatics/Genetics)-75009360-58577JC

Organization
Sanofi US
Job Location
49 New York Avenue
Framingham, MA 02142
Salary
-
Job Description

Job Responsibilities/Department Description:

 

We seek a highly motivated postdoctoral fellow to embark on a two-year research project to computationally identify therapeutic targets supported by human genetics.  You will partner with scientific colleagues in functional genomics, disease biology, and clinical research groups throughout Genzyme to design and execute a computational strategy for target identification for therapeutics discovery.  Key research aims and responsibilities of the position are to:

 

  1. Develop enhanced methods for scientific literature data mining and analysis using natural language processing tools and ontologies tailored for target identification.
  2. Identify relevant public and internal data sources for human genetic variation, gene regulation, and protein expression.  Lead data integration/aggregation efforts to support target identification.
  3. Develop an integrated computational approach leveraging scientific literature and experimental results for target identification.
  4. Develop a user interface for research and informatics scientists to browse/query  database contents and data mining results.
  5. Interface with research scientists and provide support as a genomics/informatics expert.
  6. Prepare concise and insightful presentations, reports, and manuscripts for internal and external presentations/publications.
Requirements

Basic Qualifications:

Ph.D. degree in genetics, bioinformatics, biostatistics or computational biology. Should have strong programming skills and proficiency with statistical analysis software such as R/Bioconductor, Matlab, SAS and/or JMP. Hands-on experience in GWAS, exome, or genomic sequencing data analysis is required. Broad knowledge and experience with public genetic databases (1000 Genomes, dbSNP, dbGAP, GTEX, etc.) are also required. 

Preferred Qualifications:

Hands-on experience with natural language processing tools and text mining experience is strongly preferred but not required.  Knowledge of visual analytics and workflow tools such as Spotfire, Pipeline Pilot, and/or Cytoscape is also preferred. General knowledge of methods for genomics data analysis and functional interpretation, as well as relevant functional knowledge sources, is a plus. The successful candidate should have effective interpersonal skills, a strong motivation for scientific research, and ability to collaborate successfully with colleagues along with an aptitude for problem solving and working independently.

 

About Our Organization

Post Doctoral Associate (Bioinformatics/Genetics)-75009360-58577JC

Genzyme has pioneered the development and delivery of transformative therapies for patients affected by rare and debilitating diseases for over 30 years. We accomplish our goals through world-class research, collaboration with the global patient community, and with the compassion and commitment of our employees.  With a focus on rare diseases and multiple sclerosis, we are dedicated to making a positive impact on the lives of the patients and families we serve.  Genzyme's portfolio of transformative therapies, which are marketed in countries around the world, represent groundbreaking and life-saving advances in medicine. As a Sanofi company, Genzyme benefits from the reach and resources of one of the world's largest pharmaceutical companies, with a shared commitment to improving the lives of patients.

                                                                                                                                       

Sanofi, an integrated global healthcare leader, discovers, develops and distributes therapeutic solutions focused on patients’ needs. Sanofi has core strengths in the field of healthcare with seven growth platforms: diabetes solutions, human vaccines, innovative drugs, consumer healthcare, emerging markets, animal health and the new Genzyme.

 

Genzyme Corporation (a Sanofi company) and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status, or any other characteristics protected by applicable law.

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