Elucidate phosphosignaling networks in medulloblastoma in a highly engaging post-doctoral fellowship position at the Collaborative Center for Translational MassSpectrometry.
Duties and Responsibilities:
Dr. Patrick Pirrotte, Assistant Professor and Director of the Collaborative Center for Translational Mass Spectrometry (TGen) is currently seeking to hire a Postdoctoral Research Scholar. This position involves design, execution, and supervision of technical personnel conducting experiments on the proteomics and biochemistry (signal transduction pathways, primarily phosphosignaling) underlying the invasive behavior of pediatric brain tumors, with a specific focus on medulloblastoma. The Postdoctoral Scholar will be fully embedded in a highly prolific, multi-institutional collaboration with partners in California and Europe. He/She will collaborate with other Scholars at TGen and foster relations with researchers in medulloblastoma and neuroblastoma. He/She will work closely with Dr. Pirrotte on peer-reviewed and new projects that involve co-investigators within TGen and at outside institutions. The Scholar will assume progressively more autonomous responsibilities for project development and execution with the aim of career maturation towards being an independent (extramurally-funded) scientist. The Fellow will assist in manuscript preparation, grant proposal development, and progress reports.
Projects in the laboratory include cancer-centric investigations that require competency, proficiency, and/or familiarity with (the majority of) the following,
Mission critical requirements in experimental Design, technical execution, data analysis, interpretation, and presentation of findings:
1) proteomics using mass spectrometry, phospho-PTM discovery, signal pathway analysis, protein-protein interactions;
2) cancer-related in vitro cell biology studies of mammalian cell proliferation, apoptosis, migration, and viability;
3) protein biochemistry using western blot, immunoprecipitation, densitometry, immunofluorescence, immunohistochemistry, confocal microscopy, upright epifluorescence microscopy.