The Max Planck Institute for Infection Biology (MPIIB), Department of Molecular Biology,
Berlin, Germany, is seeking for the earliest possible start date a PhD Student in Bioinformatics/Biostatistics for a project aiming to apply system biology methods to the analysis of functional high-throughput data of host–pathogen interactions.
Chlamydia trachomatis is an obligate intracellular bacterium with relevance for a number of infectious diseases and has been linked to cervical and ovarian cancers. Our lab has generated extensive high-throughput genome-wide data sets on functional, transcriptional and genomic characteristics following C. trachomatis infection. We also participate in consortia planning to generate more such data sets from various levels.
However, a systematic understanding of the interplay between several layers of host and bacterial regulation is still lacking.
We seek a highly motivated candidate to contribute to challenging projects and to establish novel methods which allow a system-wide integration of functional screens as well as transcriptomic and genomic data sets. The candidate would also be involved in the planning and, if desired, the generation of novel datasets complementing the large corpus of existing data.