NGS Data Analyst

Organization
Regeneron Genetics Center
Job Location
777 Old Saw Mill River Rd
Tarrytown, NY 10591
Job Description

The Regeneron Genetics Center is a wholly-owned subsidiary of the Company organized to collaborate with health systems and research groups to elucidate, on a large scale, genetic factors that cause or influence a range of human diseases. Building upon Regeneron's strengths in mouse genetics and genetics-driven drug discovery and development, the Center will specialize in ultra-high-throughput exome sequencing and computational biology; discovery of genotype-phenotype associations through linkage to well-annotated de-identified patient electronic medical records; and validation of discoveries using Regeneron’s VelociGene® technology. Our interests encompass a breadth of different areas such as Mendelian and family frameworks, large-scale population genetics (both common and rare variants), and gene-gene interactions. Program goals include target discovery, indication discovery, and patient-disease stratification. Objectives include advancing basic science around the world through public sharing of discoveries, providing clinically-valuable insights to physicians and patients of collaborating health-care systems, and identifying novel targets for drug development.

Responsibilities:
The NGS Data Analyst, for our Bioinformatics and Data Analysis group will report to the Manager of the Production NGS Data Analysis group and be responsible for:

• Effectively communicating with internal collaborators regarding data access, data and file format questions, and general assistance with RGC data.
• Developing NGS analysis pipelines and strategies. Constantly benchmarking and reevaluating existing pipelines with new and different tools.
• Managing the design, progression, and completion of NGS analysis projects with clear timelines, budgets, and data delivery.
• Prioritizing and managing work effort to deliver data, results, and analyses in efficient and time appropriate fashion.
• Interacting with downstream analysts to address needs and developing tools and automation enabling Analytical and Translational Genetics teams.
• Collaboration with LIMS, laboratory specialists, and analysts to deliver high-quality production data in a timely fashion.
• Tracking sample metadata, and delivering data in a high-throughput production environment.
• Providing bioinformatics support for routine sequencer maintenance and upgrades.
• Working with the sequencing vendor and the Production Manager to quickly resolve instrument problems.
• Maintaining accurate sample and sequence analysis records in our LIMS.
• Implementing standard operating procedures to maintain stringent performance requirements, including throughput and quality metrics.

Requirements

Requirements:
This position requires a minimum of a masters or graduate degree in computer science, bioinformatics, computational biology, or a life science and 4+ years of experience in a next-generation sequencing lab.

 Strong interpersonal skills and effective communication of complex concepts to collaborators with wide range of expertise.
• Interest in and ability to learn/use new Technologies and Software packages.
• Experience providing analysis support for the production of NGS sequence data.
• Comfortable with wide variety of NGS data analysis tools. PacBio experience a plus.
• Familiarity with standard molecular biology and NGS library techniques.
• Experience capturing and tracking sample meta-data.
• Script and software development experience to support NGS data analysis.


This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply today and learn more about Regeneron’s unwavering commitment to combining good science & good business.

To all agencies: Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the internet or in any form and/or method will be deemed the sole property of Regeneron, unless such search firms/employment agencies were engaged by Regeneron for this position and a valid agreement with Regeneron is in place. In the event a candidate who was submitted outside of the Regeneron agency engagement process is hired, no fee or payment of any kind will be paid.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, sexual orientation, gender identity, disability status, protected veteran status, or any other characteristic protected by law.

Students whose classmates are interested in science are more likely to think about a career in science, technology, engineering, and mathematics, a new study says.

CNBC reports that the genetic counseling field is expected to grow as personalized medicine becomes more common.

Gladys Kong writes at Fortune that her STEM background has helped her as a CEO.

Social scientists report that the image of the 'lone scientist' might be deterring US students from STEM careers.