The Broad Institute of MIT and Harvard is the world’s leading biomedical research institute dedicated to the bold mission of using the full power of genomics to transform the understanding and treatment of disease. The Broad Institute seeks to describe all of the molecular components of life and their connections; discover the molecular basis of major human diseases; develop effective new approaches to diagnostics and therapeutics; and disseminate discoveries, tools, methods, and data openly to the entire scientific community.
Founded in 2004 by Eric Lander and philanthropists Eli and Edythe L. Broad, the Broad Institute includes faculty, professional staff, and students from throughout the MIT and Harvard biomedical research communities and beyond, with collaborations spanning more than a hundred private and public institutions in more than 40 countries worldwide.
A research scientist I position focused on mouse models of mitochondrial disease is available in the laboratory of Dr. Vamsi Mootha, located at Massachusetts General Hospital and the Broad Institute. The laboratory is also part of Harvard Medical School and the Howard Hughes Medical Institute. This position, based at the Broad Institute, is a rare opportunity to be part of a dynamic team consisting of experts in biochemistry, systems biology, and clinical medicine focused on the discovery of therapeutics that target the mitochondrial basis of rare and common disease.
We are seeking a highly motivated research scientist with a strong background in mouse genetics and mouse biology, with a proven track record of productivity, and ability to work in a fast-paced and team-based setting. Technical skill, attention to detail, and excellent communication skills are a must. There will be ample opportunities for co-authorship on high-impact papers.
PRINCIPAL DUTIES AND RESPONSIBILITIES
• Generate and characterize novel mouse models of mitochondrial disease to identify features of disease pathogenesis that can be targeted therapeutically
• Use transgenic technology, viral vectors, and drug treatments to test novel therapeutic hypotheses in vivo
• Provide oversight/management of the laboratory’s mouse colony
• Plan and execute projects and experiments independently, identifying and resolving technical and methodological problems as they arise
• Attend weekly team meetings to present results, ensuring that projects support current team goals
• Train, supervise, or mentor junior group members as needed
• PhD and/or MD, with a focus on mouse models of disease
• 0+ years of related job experience. Research experience and expertise in mouse biology and genetics
• Strong record of research publications and high profile scientific presentations
• Demonstrated ability to develop and shift plans to adjust to rapidly changing scientific priorities and technologies
• Excellent communication (both in writing and presenting), analytical, and interpersonal skills
• Excellent organization and time management skills
• Ability to build excellent working relationships and foster collaboration in a team environment
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