Molecular Pathways Research Scientist (BS or MS) job

Novartis Pharmaceuticals
Job Location
Cambridge, MA
Job Description

Do you have what it takes to help us address monogenic diseases? We are seeking a passionate, energetic scientist with B.A./B.S. or M.S. degree to join the Biology group in the New Indication Discovery Unit (NIDU) in the Novartis Institutes for Biomedical Research in Cambridge, MA. The scientist will participate in the characterization and progression of small molecule candidates and ex vivo gene editing approaches to address severe genetic diseases with high unmet medical need. EEO Statement The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or any other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, marital or veteran status, disability, or any other legally protected status.

• M.S. or B.A./B.S. in Molecular Biology, Cell Biology, Genetics or related discipline with minimum 5 years work experience
• Experience with cell-based models of disease, cellular and biochemical assays
• Experience with small molecule screening and support of compound progression
• Experience with in vivo models of disease or genetic model organisms, ideally including pharmacology studies
• Proficiency in the use of transfection and viral transduction technologies and genome editing approaches such as CRISPR/Cas9, as well as genetic knockdown techniques including RNAi
• Proficiency in molecular biology, including cloning strategies, site-directed mutagenesis, construction of reporter systems, design and use of various expression vectors and measurement of protein and mRNA expression
• Demonstrated ability to evaluate and implement new techniques, work in a collaborative team environment and handle multiple tasks efficiently
• Attention to detail and proven track record in handling, quantitatively analyzing and recording experimental data

How to Apply

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