Medical Science Liaisons Leader

Spark Therapeutics
Job Location
Philadelphia, PA
Job Description

The Head of Medical Science Liaisons (MSL) will be responsible for helping to build and lead Spark MSL team(s). This position will define the objectives of the MSL function, including building medical and scientific advocacy, and providing medical support for potential treatment centers of excellence for Spark investigational and approved products. 


•Oversees and leads the Spark US MSL function. Manages and mentors individual MSLs, providing ongoing communication and feedback. Responsible for performance management and professional development of MSL team members. 
•Identifies MSL activities in the field, particularly at potential treatment centers of excellence for Spark investigational and/or approved products 
•Ensures development of training materials and communication tools for MSLs to support education of field-based retinal specialists, pediatric ophthalmologists and other key medical audiences about gene therapy, inherited retinal dystrophies (IRDs), the importance of genotyping and scientific data and advances in this disease state. May cover other disease states and therapeutic areas as necessary, including hemophilia. 
•Acts as internal liaison to ensure that strategic direction and timely information is communicated to the MSL team, and that MSL feedback from KOL and other medical community interactions is incorporated into medical strategy and MSL contributions are recognized appropriately 
•Participates in medical congresses, scientific advisory boards, regional events and patient advocacy meetings as appropriate to further define and lead appropriate MSL activities in these venues 
•Maintains business and clinical knowledge of the Spark Therapeutics treatment landscape including current treatment strategies, current and pending competitors, and new therapeutic developments. 
•May collaborate with clinical team and CRA's to coordinate and optimize educational and research support for sites/investigators participating in Spark Therapeutics’ clinical trials. 
•Identifies and communicates key clinical and research issues and insights from industry leaders to appropriate departments to help shape company research, development, and strategies for investigational and commercialized products. 
•Maintains clinical expertise through comprehensive education including attendance at relevant symposia, scientific workshops, and review of key journals. Participation in required internal training, presentations and journal clubs. 
•Adheres to regulatory and compliance guidelines and company policies in all aspects of scientific dissemination of information to include responses to unsolicited requests for medical information. 
•Represents Spark in a professional, ethical, compassionate, and scientifically credible manner at all times. 
•Addresses administrative and reporting needs in timely and organized fashion


•Ability to manage and mentor field-based team members. Deep experience with the MSL function and compliance requirements regarding HCP interactions, scientific exchange, requests for off-label information and other relevant areas 
•Demonstrated ability to define MSL objectives, and provide vision and an innovative approach to leveraging field-based resources to support a novel treatment in a rare disease area 
•Ability to manage moderate to heavy administrative duties including travel and calendar management, independently arranging frequent meetings with field-based team members 
•Ability to interpret and translate data and complex scientific concepts into clinically relevant messages 
•Understanding of highly regulated pharmaceuticals environment. 
•Ability to initiate and maintain relationships with medical community. 
•Excellent written and verbal communication skills and presentation skills required


•MD, PharmD, PhD (clinical sciences or Healthcare administrative) strongly preferred 
•A minimum of 5 years of MSL leadership experience desired; rare disease and/or biotech experience strongly preferred 
•Specific experience in and knowledge of ophthalmology, particularly retinal disorders, desirable. 
•Clear understanding of medical practice, healthcare systems and clinical decision making guidelines as they impact patient care 
•Travel 40% or greater, including domestic and international travel as needed.

Transforming Patient’s Lives.
Spark Therapeutics is a pioneering gene therapy leader transforming the lives of patients suffering from debilitating genetic diseases by developing one-time, life-altering treatments. We are embarking on our goal to deliver the first approved gene therapy product in the US for genetic blinding conditions and have a product pipeline addressing other unmet rare genetic diseases. We have an entrepreneurial culture and are looking for talented and passionate professionals who are committed and motivated to making a difference in the lives of our patients. If you share our passion for excellence and are looking for a dynamic work environment that fosters creativity, scientific innovation and team collaboration, you may be a great fit for our team. 


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