Manager of Next Generation Sequencing | GenomeWeb

Manager of Next Generation Sequencing

Mount Sinai Genetic Testing Lab - Connecticut
Job Location
Branford, CT
Job Description

 • Oversee and contribute to generation of large, multiplexed pools of amplicons and libraries from isolated gDNA using automated methods in a diagnostic laboratory setting. 

• Ensure accurate and timely entry of sample information into Laboratory Information Management System (LIMS). 

• Oversee and develop library construction and Next Generation Sequencing protocols using automated methods and perform Next Generation Sequencing (NGS). 

• Using established Standard Operating Procedures (SOPs), oversee library handling, tracking, and storage. 

• Use a keen attention to detail to maintain sample integrity and identification throughout entire workflow. 

• Strict adherence to local, regulatory, and quality management guidelines to ensure full compliance.

• Help guide technology transfer from MSSM R&D into production environment.

• Train new hires.


• Bachelor’s degree in life science-related discipline. 

• Experience in safe handling and disposal of potentially infectious clinical specimens in a biological safety level laboratory environment.

• 5+ years experience with standard molecular techniques:

- PCR, qPCR, electrophoretic methods, DNA quantification, purification, and pooling methods, enzymatic manipulations, and primer design. 

- Preference will be given to those applicants with previous NGS library experience. 

- Experience with operating and programming liquid handling systems is preferred. 

• 2+ years experience operating NGS systems. Experience with multiple platforms is a 


• Experience with developing and/or performing high complexity lab-developed tests 

(LDTs) is a plus. 

• Experience in a CLIA/CAP-accredited facility is preferred.

How to Apply

Send a cover letter and resume to:


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