Manager, Clinical Genomics Laboratory (CLIA)

The Jackson Laboratory for Genomic Medicine
Job Location
Farmington, CT
Job Description

About The Jackson Laboratory for Genomic Medicine: Comprising 183,000 square feet of highly advanced, state-of-the-art laboratories and supporting facilities, JAX-GM is conveniently located midway between NYC and Boston, in the heart of Connecticut. JAX-GM is part of an exciting, internationally-recognized research and educational institution with unparalleled genomic resources and research support services.


About the position: This position manages the wet lab operations and personnel in the Clinical Genomics Laboratory (CGL) at JAX Genomic Medicine. Primary responsibilities include maintaining technical quality standards, overseeing day-to-day operations, managing throughput of the laboratory sample processing, and meeting all regulatory (CLIA/CAP) requirements.  The incumbent is responsible for development, implementation and clinical validation of new methods and instrumentation, including high-throughput sequencing (HTS) and other related genomic technologies.

This position requires a high degree of technical abilities in DNA and RNA analysis as would be performed in a molecular diagnostics and/or production laboratory, as well as leadership skills to develop personnel and guide them in their development and operational roles. The position also requires administrative duties such as laboratory reports, management of quality metrics, and regular personnel meetings.




  • Manage the operations of the laboratory technicians while providing mentorship and coaching. Establish and track annual goals and performance review. Assign group resources to processes/projects maximizing throughput and quality.
  • Directly oversee efficiency, documentation, SOP’s, and general lab activity of the clinical genomics laboratory. Develop/implement process control and QA/QC measures and ensure personnel follow prescribed SOP's and practices. Generate monthly, quarterly, and annual metrics reports and work with the financial analyst to maintain accurate costing models of service offerings and development projects. Successfully sustain CLIA/CAP certification, including competency and proficiency assessments, for molecular diagnostics laboratory.
  • Coordinate implementation and clinical validation of new services/instrumentation and improvements to existing processes. Perform/assign/interpret experiments addressing the implementation of new methods and/or instrumentation into the service. Collaborate with other groups internal and external to JAX as needed to coordinate molecular data analysis practices including the investigation and development of tools and methods. Be kept abreast of advances in the field, evaluating alternative methodologies and implementing them to improve the quality of current services or to provide new services.
  • Work at the bench processing samples as needed for production, personnel training, and development projects.
  • Participate/ facilitate meetings with external as well as internal JAX constituencies for the clinical lab. Project Management including coordination, collaboration and presentation of pertinent information for cross-functional projects through customer calls, project summaries, meetings and lab tours.
  • A degree in genetics, genomics, translational research, molecular biology or similar biological discipline is required:
    • Bachelor’s degree with 10 years of direct clinical genomic testing experience; OR
    • Master’s degree with 5 years of direct clinical genomic testing experience.
  • ASCP Certification in Molecular Biology preferred; or commitment to get certified within one year of onboarding.
  • Demonstrated success in laboratory operations, troubleshooting, and resource allocation with HTS and other common molecular genetics technologies (such as Sanger sequencing) is required.
  • Demonstrated experience in evaluation and implementation of new methods/technologies in a CLIA-certified laboratory is required.
  • Demonstrated leadership through successful project ownership, training and mentorship required. 1-2 years in a formal leadership role is preferred.
  • Excellent interpersonal, verbal, and written communication skills; strong organizational and analytical skills; and the ability to work in a highly cooperative team environment as well as independently.
  • Critical thinking skills and the ability to rapidly troubleshoot in order to overcome technical challenges.
How to Apply

Application link:

About Our Organization

JAX began in 1929 with a small group of scientists dedicated to the emerging field of genetics. We now have over 1,700 scientists, technicians, and support staff, including over 50 Principle Investigators in five primary disease areas: cancer, reproductive biology, immunology, metabolic processes and neuroscience. Our fundamental contributions to biomedical research include cancer genetics and establishing the mouse as the premier research animal model.

  • Uncover more of our historic milestones, including the 26 Nobel prizes associated with our research, resources, and education
  • Read our latest news & insights for a glimpse at how we’re impacting the future of biomedicine
  • Follow the progress we’re making on our quest to improve human health via our recent research highlights


EEO: All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability or protected veteran status.

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