Instrument Software Engineer

Twist Bioscience
Job Location
San Francisco, CA
Job Description

Programmable DNA, the software of Life, is finally here! Twist Bioscience is developing a disruptive Synthetic DNA technology that will change the world, enabling widespread health and sustainability. Synthetic biologists will use our products to engineer how organisms produce cures to diseases, everyday chemicals are made using the atmosphere as the carbon source, plants make their own fertilizers, in-vivo diagnostics will alert us when we are sick, and many more applications. 

The Instrument Software group at Twist is a small team with a very big impact. Our team develops the software suite that runs multiple custom instruments and tightly integrates with back-end web services and bioinformatics pipeline. 

As an Instrument Software Engineer, you will be developing software for our custom instruments and working on system bring-up and design validation in a multidisciplinary environment with hardware engineers, chemists, and biologists. This position focuses on C# and C++ development with a dash of other technologies such as JavaScript and HTML.  


  • Work with team members, chemists and biologists to flesh out features and sprints
  • Take ownership of features / projects
  • Develop pragmatic and maintainable software using best practices
  • Participate and run design / code reviews
  • Document work and use version control system effectively

 Required qualifications:

  • BS in Computer Science or related technical field
  • 5+ years experience in C# and C++
  • Mastery of object oriented programming concepts, and clean software architecture design
  • Image processing background
  • Experience with Git or similar version control systems

 Preferred qualifications:

  • Master's or PhD in Computer Science or related technical field
  • Electrical and mechanical engineering experience is a big plus
  • Experience with the latest .NET is a plus
  • WPF experience is a big plus, and an eye for clean UI design is greatly appreciated
  • Interest and ability to learn other programming languages as needed
How to Apply

Please apply directly at:

About Our Organization

About Twist Bioscience

Twist Bioscience is a privately-held venture-backed company. The two key investors are ARCH Venture Partners and Paladin Capital Group. The founders of Twist Bioscience are proven entrepreneurs and innovators in the genomics field. Our expertise is synthetic DNA. We have developed a proprietary semiconductor-based synthetic DNA manufacturing process featuring a 10,000-well silicon platform capable of producing synthetic biology tools, such as oligonucleotides, genes, pathways, chassis and genomes. By synthesizing DNA on silicon instead of on traditional 96-well plastic plates, our platform overcomes the current inefficiencies of synthetic DNA production, and enables cost-effective, rapid, high-quality and high throughput synthetic gene production. The Twist Bioscience platform has the potential to greatly accelerate the development of personalized medicine, sustainable chemical production, improved agriculture production as well as new applications such as in vivo diagnostics, biodetection and data storage. For more information, please visit Twist Bioscience is on Twitter. Sign up to follow our Twitter feed @TwistBioscience at

Twist Bioscience is an equal opportunity and e-verify employer.

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