Informatics Post-Doctoral Fellow

HudsonAlpha Institute for Biotechnology
Job Location
601 Genome Way
Huntsville, AL 35806

HudsonAlpha offers a competititve benefits package.

Job Description


The Informatics Group led by Dr. Worthey is multi-disciplinary, comprising research scientists, software developers, informaticians, and computational scientists with a reputation for excellence within the fields of Informatics and Genomics.  The focus of the group is 1) identifying and understanding the molecular basis for human disease and 2) application of scientific findings to support selection and alteration of clinical treatment plans in patients. The team is actively engaged with basic, translational, and clinical scientists as well as clinicians and is part of a number of genomic medicine programs including the NIH Undiagnosed Disease Network.


Successful Post-Doctoral candidates will have the opportunity to develop new projects at the interface between big data analytics and genomic medicine. Projects may include tool and algorithm development, development of novel and robust analytical methodologies, and application of these methods and tools to support interpretation of molecular changes in individuals and patients with genetic disease. They will be expected to apply methods for integrative analysis of data, including clinical data, at scale. Potential projects will span rare and common disease including adult and pediatric diseases and oncology. Multiple positions are available.


The Informatics Team at HudsonAlpha Institute for Biotechnology is seeking Post-Docs who:

  • Will assist in interpretation of data to enhance understanding of human disease.
  • Will assist in interpretation of clinical data to assist in diagnosis and clinical decision making.
  • Will collaborate with physicians, computational scientists, and biologists within our genomic medicine programs.
  • Work well in a team environment.
  • Have a strong desire to learn and implement new analytical methods.
  • Will perform other duties as assigned.                  
  • A background in biology is desired but not necessary.


Education and Experience: 

  • A Ph.D. in Informatics, Genetics, Biostatistics, Computational Biology, or related fields is desired.
  • A degree in Computer Science or similar field with the willingness to learn biology is also acceptable.
  • Candidates should be comfortable working on UNIX/Linux operating system.
  • Proven skills in programming languages such as c/c++, Java etc. is desired.


Required Skills:

  • Experience with clinical or translational analysis of high throughput sequencing data, or other high-throughput datasets is desired for one of these positions.
  • Experience with phenotype ontology development and/or text mining would be beneficial for one of these positions.
  • The ability to analyze and interpret results and to communicate findings with others and produce scientific publications is required.
  • This is a highly collaborative multidisciplinary environment; good communication and organizational skills are a must.


The physical requirements and environmental conditions of this position consist primarily of:

  • Continuous mental and visual attention.
  • Ability to work at a computer monitor for significant portions of the workday.
  • On-call availability and periodic overtime.



About Our Organization

INSTITUTE OVERVIEW                                         

HudsonAlpha Institute for Biotechnology is a genomic science and applications nonprofit organization. It is a high-volume genomic data producer and a global scientific collaborator valued for genomic data analysis and interpretation to solve questions in cancer, undiagnosed childhood genomic disorders, neuro-psychiatric disorders, immune-mediated disease, agriculture and more. Its unique campus crosses the boundaries between scientists, educators, and commercial business to spark innovation and growth.

Patricia Fara writes about childcare funding, and women in science and science history at NPR.

National Institute of Environmental Health Sciences researchers have visualized the career paths of former postdocs.

A new survey from the Pew Research Center finds that half of women working in STEM have experienced gender discrimination at work.

A proposal to tax students' tuition waivers no longer appears in the US tax bill, Vox reports.