The field of single cell genomics is moving at a very rapid and exciting pace. Many methods go beyond single cell RNA-seq to study upstream processes in the regulation of RNA production. The field is advancing to measure multiple parameters from the same single cell (multi-omics) and to study cells in their native in-situ context. The latter, spatial single cell omics, often involves imaging-based methods rather than sequencing, including highly multiplexed fluorescent in-situ (FISH) hybridisation.
To help scientists stay at the forefront, the Genomics Technology Development Team will optimise and develop new single cell and spatial genomic technologies, leveraging current genomics and imaging expertise within the institute. The group will scope out new technologies and react to needs within the institute, focusing on optimising and developing technologies for use in complex tissues and embryos. Through training of students and postdocs in different labs, these methods will be transferred to research groups throughout EMBL. The head of the team will therefore bridge between research groups and EMBL core facilities.
You will lead a team of scientists/technicians to develop and optimise single cell and spatial omic protocols for use by research groups throughout EMBL. You will perform hands on experiments, as well as managing the work of others within your team. You will report to the head of the Genome Biology department and the head of Core Facilities. The team will focus on internal needs within the institute, optimising techniques that can then be used by students and post-docs throughout EMBL. Part of the role will therefore be hands on training of students and post-docs once a technique is optimised, and helping to transfer technologies to the core facilities once they are routine. This is a technology development focused role, while the biological questions and running of projects will come from research groups.