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Head of Assay Development

Organization
Molecular Diagnostics Company in Stealth Mode
Job Location
La Jolla
La Jolla, CA 92037
United States
Benefits
  • Salary with significant bonus potential in future years
  • Founder-class Equity grant package
  • Comprehensive health and wellness benefits package
  • Startup-friendly employee perks
  • State-of-the-art facility with On-site Gym, Parking, Farm-To-Table Restaurant, and Office Snacks and Beverages (Nespresso!)
Job Description

Job Description

We are looking for a Head of Assay Development who will be responsible for leading the development of novel, multi-omic assays for veterinary applications.

 

Liquid biopsy approaches leveraging the power of next generation sequencing (NGS) and other emerging technologies are poised to revolutionize human oncology in coming years. We aim to do the same for the veterinary space – faster, and with no compromise in quality and scientific integrity. We are developing liquid biopsy assays for the detection, characterization, and management of cancer in pets, starting with dogs – who have a 10x higher annual incidence of cancer compared to humans. If you love pets and cutting-edge science, you will fit right in.

 

Key Duties and Responsibilities

Build and lead a team developing cutting-edge, high-throughput molecular assays using genomic and proteomic approaches in a laboratory that aims to approximate CAP/CLIA standards for veterinary applications.

 

Lead the assay design and validation process from project inception and scoping through product launch, including:

  • Content selection to match envisioned clinical use cases;
  • Assay design (optimized for performance, quality & reliability, and efficiency);
  • Validation study design and sample selection;
  • Hands-on analytical/clinical/end-to-end validation in the laboratory;
  • Workflow and SOP development; and
  • Tech transfer to clinical lab team.
  • Ensure compliance with applicable regulatory requirements.
  • Collaborate with cross-functional teams to determine product requirements.
  • Manage projects and day-to-day operations of the laboratory R&D staff.
  • Author analytical and clinical validation internal summaries as well as manuscripts intended for publication in peer-reviewed journals.
  • Perform hands-on experiments as necessary, and train / supervise staff in the performance of such experiments.
  • Assist with development of automation processes.
  • Provide flexible support for other activities including emerging technology assessment, LIMS consulting, instrument troubleshooting, etc.
  • Mentor and direct scientific laboratory staff.
  • Manage CROs, contractors, and other parties that provide external support for Assay Development processes.
Requirements

Education

  • PhD, DPhil, MD, or equivalent doctoral degree required.

 

Requirements and Qualifications

  • 6+ years of experience with high-complexity molecular assay development (under design control) and assay validation experience required.
  • Experience with all aspects of next-generation sequencing workflows, including DNA/RNA isolation and library preparation using both off-the-shelf and custom-made approaches.
  • Experience in a clinical laboratory (CAP accredited and/or CLIA certified) highly desirable.
  • Project management experience required, including experience managing timelines and budgets.
  • Highly organized and systematic, exceptional attention to detail, and ability to complete tasks with a high degree of accuracy.
  • Must have experience managing a team and collaborating with cross-functional groups.
  • Proven ability to learn new skills quickly and adapt to new processes smoothly. High tolerance for ambiguity, and ability to work effectively in a rapidly changing startup environment.

 

Location

  • The position is based at Company HQ in La Jolla, San Diego
  • Domestic and international travel (5-15%)
How to Apply

How to Apply

Please send statements of interest, resume and background materials to [email protected]

 

EQUAL OPPORTUNITY EMPLOYMENT: We are proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.

NOTE TO EMPLOYMENT AGENCIES: We value our relationships with our Recruitment Partners and will only accept resumes from partners who have been contracted by a representative of our Company to collaborate with us. We are not responsible for any fees related to resumes that are unsolicited or are received by any representative of our Company.

About Our Organization

Our Organization

Molecular Diagnostics Company in Stealth Mode

13 Employees & Founded in 2019 / Delaware Incorporated, Based in La Jolla, CA

Who We Are

The Company is a venture-backed San Diego based genomics/molecular diagnostics startup focused on the development of breakthrough non-invasive liquid biopsy tests for the early detection, characterization, and management of cancer in a hitherto unexplored and novel area with tremendous commercial and scientific potential. We have a highly innovative approach to the science, with cutting-edge assays that are customized for the target genome and innovative next-generation sequencing (NGS) based techniques. We aim to revolutionize the detection and ultimately treatment of cancer for this vast target population.

 

The Company’s founding team and advisors include more than a dozen former senior executives from Illumina, Sequenom, PGDx, LabCorp, Pathway Genomics, J&J, and more. Most of them hold MD, PhD, MS, DVM, or MBA degrees, and have been affiliated with prestigious academic institutions including Cornell, Harvard, Johns Hopkins, MIT, Stanford, UCSF, UCLA, University of Michigan, UC Berkeley, UCSD, University of Oxford and Yale.

 



 

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