Fully funded PhD studentship in genomics (Royal Veterinary College, London)

Royal Veterinary College
Job Location
Royal College Street
United Kingdom

The student will join a vibrant research group with lots of experience and expertise in comparative animal genomics and will have a chance to contribute to several large international genomics projects led by Broad Institute, Sanger Institute and the Ten thousand genomes (G10K) community of scientists. They will obtain complementary training in bioinformatics, wet lab techniques and scientific presentations to develop skills for a successful genomics-oriented career in biology.

Job Description

Dr. Denis Larkin's group at the Royal Veterinary College, University of London currently has a three year fully funded PhD studentship position in animal genomics available for EU applicants. Applicants from other countries please see conditions below.

Mammalian and avian chromosomes drastically differ in structure and evolutionary stability. While avian genomes tend to be small and structurally similar across the majority of avian species, the mammalian genomes are about three times larger and often differ in chromosome structures even among closely related species. This PhD programme will investigate the evolutionary basis of this difference and its implication on phenotypic diversity in the two animal classes. To achieve this the student will first develop and apply a novel technique for a fast improvement of fragmented mammalian genomes to complete chromosome assemblies to make them suitable for comparison with other genomes. This part of the project will focus on several species of neglected agricultural and biomedical importance. The genome assemblies produced by PhD student will then be combined with other genomes of suitable quality and compared to genomes from two phylogenetic Classes: mammals and birds. The student will focus on distribution of genomic features that are likely be related to evolutionary stability of avian genomes and structural dynamics of mammalian genomes. Among other features these will include genes, transposable elements, conserved non-coding sequences. The student will test the hypothesis that distribution of these features contributes to stability and evolutionary dynamics of animal genomes.

The studentship will commence in October 2018.


Desirable requirements:

Experience in bioinformatics (analyzing large datasets, programming, or data visualization).
Experience in genomics.

This is a three year fully funded studentship. It is open to UK/EU applicants only. International students are welcome to apply but must be able to pay the difference between UK/EU and international tuition fees.

How to Apply

We welcome informal enquiries - these should be directed to: dlarkin@rvc.ac.uk

To apply please follow short link: http://goo.gl/ZgNnkA

Deadline for applications: 13/02/2018

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