The Jackson Laboratory is inviting applications for Assistant, Associate and Full Professors in Cancer Research at both The Jackson Laboratory for Mammalian Genetics campus in Bar Harbor, Maine, and The Jackson Laboratory for Genomic Medicine campus in Farmington, Connecticut.
We are seeking faculty who are taking computational, molecular, genomic, cellular, organismal and/or systems approaches in the following research areas:
• Progenitor cell biology
Current research in the JAX Cancer Center includes cellular and genomic defects in tumor repopulating cells; the stem and progenitor cell-of-origin for cancer; epigenetic control of cell fate determination and its role in malignancy
• Cancer immunology
Current research in the JAX Cancer Center includes tumor-immune system interaction and its relevance to cancer therapy; the immune microenvironment and its effect on tumor development; hematologic cancers
• Mechanisms of cancer progression and evolution
Current research in the JAX Cancer Center includes mechanisms of tumor evolution; genomic and genetic instability in cancer; mechanisms and consequences of tumor heterogeneity; genetics of host-tumor interactions
• Mechanisms of drug action and therapy resistance
Current research in the JAX Cancer Center includes biology of de novo and acquired therapy resistance; influence of microenvironment on therapy response or resistance; genetics of host sensitivity to cancer therapeutics
• Cancer model development
Current research in the JAX Cancer Center includes development of novel cancer models, especially new xenograft platforms and technologies; innovative uses of genome editing technologies to build cancer models; use of complex genetic tools for cancer discovery; application of models to test novel cancer therapies
Successful applicants will enjoy access to JAX’s extensive, professionally staffed scientific resources including innovative gene editing and single cell genomic technologies, novel genetically diverse mouse populations, enhanced immunodeficient mouse platforms and model development capabilities, and advanced bioinformatics and computing infrastructure.