Experimental Officer in Bioinformatics/Biostatistics

Organization
University of Birmingham
Job Location
School of Biosciences
University of Birmingham, Edgbaston
Birmingham
West Midlands
B15 2TT
United Kingdom
Salary
£29,301 to £38,183, with potential progression once in post to £40,523 a year.
Job Description

To contribute significantly to the excellence of the NERC Biomolecular Analysis Facility – Birmingham (NBAF-B), the UK’s national research centre for Environmental Metabolomics. In particular to develop and apply expert analysis of large-scale mass spectrometry and NMR spectroscopy metabolomics datasets, including experimental design, data processing, statistical analysis and/or network analysis; to liaise with collaborating environmental scientists; to contribute to the Birmingham Metabolomics Training Centre; and to undertake independent research in bioinformatics/biostatistics. 

  • To conduct specialised computational analyses to process challenging environmental metabolomics datasets within NBAF-B, including of mass spectrometry and NMR metabolomics datasets.
  • To conduct statistical analyses of large-scale environmental metabolomics datasets within NBAF-B, including of mass spectrometry and NMR metabolomics datasets; analyses will minimally include a range of multivariate (e.g., PCA, PLS-DA, PLS-R) and univariate statistical methods.
  • To undertake independent research in bioinformatics/biostatistics within metabolomics, for example to further develop the workflows for managing and analysing metabolomics datasets, optimising spectral processing, developing tools for the interpretation of metabolic spectra or for metabolite identification, and/or Galaxy workflow development.
  • To develop and maintain the computer hardware and software associated with NBAF-B.
  • To provide training in the analysis of metabolomics data specifically through the Birmingham Metabolomics Training Centre.
  • To assist visiting scientists with the analysis of metabolomics datasets.
  • To contribute to the day-to-day operation of NBAF-B, including project design and troubleshooting, the prioritisation of data analyses.
  • To disseminate research findings through contribution to peer-reviewed publications.
  • To present research findings at conferences in the form of talks/posters.
Requirements

• PhD or equivalent experience in Bioinformatics, Biostatistics, Chemometrics or Metabolomics (all with metabolomics or related specialism). 
• Experience in the application of statistical / computational methods to the analysis of metabolomics datasets (both mass spectrometry and NMR spectroscopy based). 
• Experience in a range of statistical analysis methods, including multivariate and univariate methods. 
• Experience in programming, specifically Matlab, R and/or Python. 
• Experience in managing multiple projects simultaneously. 
• Excellent communication and interpersonal skills, including the ability to communicate complex information clearly. 
• A high level of accuracy and attention to detail. 
• Ability to work on own initiative, manage time effectively, progress tasks concurrently and work to deadlines. 
• Detailed knowledge of office safety. 
• Ability to assess resource requirements and use resources effectively.

How to Apply

Visit the UoB job section at the following link, download and review a full Job Description, and click "Apply Now".

https://atsv7.wcn.co.uk/search_engine/jobs.cgi?SID=amNvZGU9MTYyNDg4MCZ2d...

About Our Organization

The Metabolomics Initiative at the University of Birmingham began in earnest in 2003 and now encompasses several Schools including Biosciences; Geography, Earth & Environmental Sciences; Medicine; Mathematics and Computer Science. Our metabolomics research spans the development of analytical and bioinformatic methods as well as their application to wide ranging and numerous projects in the Life Sciences. These include studies in mammals, fish, invertebrates, microbes and plants, with a particular emphasis in both environmental metabolomics and clinical metabolomics. The bioanalytical facilities and expertise in both NMR spectroscopy and mass spectrometry at Birmingham are world class and include the Henry Wellcome Building for Biomolecular NMR Spectroscopy with four 600 MHz, one 800 MHz and one 900 MHz NMR spectrometers; Phenome Centre Birmingham with two 600 MHz Bruker NMR spectrometers and twelve Thermo and Waters LC-MS(/MS) for untargeted and targeted metabolite analyses; and the Advanced Mass Spectrometry Facility with Thermo Orbitrap Elite, Q Exactive and TSQ Vantage mass spectrometers (see below). The bioinformatic facilities and expertise at Birmingham include the new Centre for Computational Biology and several high performance computing clusters (details below). Our current and highly active research programme involves ca. 30 principal investigators, postdoctoral researchers and PhD students in metabolomics.

 

 

 

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