Director/Senior Director, Bioinformatics

Omniseq, LLC
Job Location
700 Ellicott Street
Buffalo, NY 14203
Job Description

The individual in this position will be responsible for developing and validating OmniSeq's molecular diagnostic and next generation sequencing analysis pipelines. This individual will also play a central role in evaluating and implementing new lab testing approaches and strategies for the company's evolving product portfolio.

 The Director – Senior Director, Bioinformatics will interact extensively with internal and external stakeholders, overseeing and/or directly contributing to clinical study planning and analyses.  He will also interact heavily with the scientific advisory board.  He will be expected to provide informatics and analytical expertise throughout the company and will be consulted extensively by associates, providing strategic input as appropriate.

  • Primary Responsibilities 

  • Lead the development of a molecular diagnostic and next generation sequencing analysis pipeline; will be expected to lead a team of other bioinformaticians and support staff and lead the interaction of this team with other OmniSeq teams

  • Develop and validate tools for statistical analysis of cancer sequencing information

  • Work closely with the clinical team and the assay development team     

  • Monitor, identify, and help solve problems which arise during conduct of clinical studies affecting data management and data analysis

  • Keep senior management team informed of progress and issues impacting project goals

  • Manage outsourcing of clinical data management arid statistical analyses, including reviewing and approving contracts, scope of work and budgets, as well as providing technical expertise in audits

  • Serve as an influential member of the leadership team


Primary Requirements


  • MS in Bioinformatics, Computational Biology or closely related fields, PhD highly preferred

  • Minimum of 5 years relevant work experience with next generation sequencing analysis

  • 2+ years of management with at least 1 direct report

  • Experience with Ion Torrent sequencing platform required

  • Proficient in programing languages such as Python, BASH, etc.

  • Experience with other aspects of information technology preferred

  • Experience with database management and programming such as MySQL, Oracle, etc. preferred

  • Position requires individual to reside in Buffalo, NY

  • Must be eligible to work in the U.S. as sponsorship is NOT available

How to Apply

To apply please send resume to Colleen Scharf, VP of Operations at [email protected]

About Our Organization

OmnSeq's vision is to find the right drug or the right clinical trial for every patient. Founded in 2015, our mission is to deliver superior results by improving access to better cancer treatment options through comprehensive molecular profiling. OmniSeq is a subsidiary of Roswell Park Cancer Institute (RPCI) in Buffalo, New York. The company emerged from the RPCI Center of Personalized Medicine.

RPCI was the first institution to focus exclusively on cancer research and continues to be at the center of groundbreaking cancer research for more than a century. This includes initiating the first experiments in chemotherapy in 1904, becoming America’s First Comprehensive Cancer Center and providing the source — RP11 (RP stands for Roswell Park) — for much of the BAC clone library used in the Human Genome Project. The breakthrough research, scientific expertise, and commitment to improving patient care is the foundation of OmniSeq today.

Find out more at

New study finds bias against female lecturers among student course evaluations, the Economist reports.

A research duo finds that science and technology graduate students who turn away from academic careers do so because of changes in their own interests.

Students whose classmates are interested in science are more likely to think about a career in science, technology, engineering, and mathematics, a new study says.

CNBC reports that the genetic counseling field is expected to grow as personalized medicine becomes more common.