Director, Genomic Technologies | GenomeWeb

Director, Genomic Technologies

Organization
The Jackson Laboratory for Genomic Medicine
Job Location
10 Discovery Drive
Farmington, CT 06032
Job Description

The Jackson Laboratory for Genomic Medicine in Farmington, CT is seeking an Associate Director / Director of Genome Technologies for multi-campus operations of the JAX Genome Technologies core. Responsibilities include operational oversight of Production Sequencing Operations (library prep and sequencing), Validation and Scale-up operations. The incumbent is responsible for management of customer, vendor and collaborator interactions as well as capacity management across campuses including outsource providers. The incumbent will provide consistent delivery of state-of-the-art, quality, and timely, cost effective sequencing services. In this role, the incumbent will be responsible for the management of operational and capital resources within budget targets. They will also be responsible for delivering effective staff development.

Responsibilities:

JAX Genome Technologies Operations – GT Production Sequencing

  • Oversees personnel (PhD Level Manager and technical staff), infrastructure and processes of the integrated production sequencing operations in Bar Harbor and Farmington support all three JAX campuses library preparation and sequencing needs.
  • Assures operations meet quality production metrics:

 High-quality sample preparation

 Platform down-time is minimal

 Platform utilization is optimized

 Turn-around-times are met

 Data quality from all platforms meets specification

 Achieves desired cost per/base targets

 Positive customer experience

  • Assures JAX (research faculty programs and collaborators) have access to the most innovative, cost effective and timely sequencing services which meet defined quality standards. Continuous evaluation of competitive service providers and engagement of outsourcing as needed.


JAX Genome Technologies Operations – GT Validation and Scale-up

  • Oversees personnel (PhD Level Manager and technical staff), infrastructure and processes of the GT validation and scale-up group, which assures transition of relevant, current and emerging genomics platforms, technologies (sequencing and counting/detection) and applications into GT Production Sequencing.

 Oversees installation and operational validation of new/incoming platforms

 Validates protocols on newly acquired platforms

 Scales protocols and established SOPs for production operations

 Adapts research protocols for scaled delivery with SOPs in production operations

 Optimizes chemistry and protocols for cost efficiency in production operations

 Smoothly transitions platforms and processes to Production Operations

 Aids in troubleshooting

 Support NGS technology R&D as needed.

  GT Operations – Overall

  • Supports users in experimental design including guidance on sample processing, library preparation and sequencing methods.
  • Responsible for oversight of JAX-GT LIMS operations and maintenance.
  • Directly interfaces with JAX-IT and Computational Sciences to assure data integrity, transfer and analysis.
  • Aligns GT operations with JAX needs

                  Assure the scientific competitiveness and differentiation of these services

                     Provides consultative services for experimental design and downstream interpretation.

                  Assures adequacy and currency of GT/MS information management (data QC, integrity,

transfer, storage) & analysis systems and integration with Computational Sciences & IT

  • Assures high-fidelity operations

 Subject matter expert for quality issues

  • Support NGS technology R&D as needed
  • Achieves operational financial targets
  • Develops individual skills and cultivates leadership within GT/MS

 

 

Requirements
  • PhD in relevant biomedical field (e.g. Genomics, Molecular Biology, Biochemistry, Chemistry)
  • Demonstrated experience in evaluating and implementing genomics technologies
  • Established genomics scientist with NGS experience (>5 years)
  • Prior experience running genome center laboratory operations (>3 years)
  • Demonstrated collaborative effectiveness
  • Ability to manage finances for both budget neutral core operations.
  • Knowledge of the supervisory processes and leadership skills acquired in at least 5 years supervisory experience.
  • Successful grant/ proposal and publication preparation
  • Excellent verbal and written communication skills
How to Apply

Please forward a cover letter and and your resume to www.jax.org/careers, requisition #4829.

About Our Organization

The Jackson Laboratory is an independent, nonprofit biomedical research institution based in Bar Harbor, Maine, with a facility in Sacramento, Calif., and a new genomic medicine institute in Farmington, Conn. We employ more than 200 Ph.D. scientists and a total of more than 1,400 employees. In 2011 and 2012, researchers voted The Jackson Laboratory among the world’s top 15 “Best Places to Work in Academia” in a poll conducted by The Scientist, a magazine for people working in the life sciences. The Laboratory draws on an 83-year reputation for excellence in mammalian genetics, built on the groundbreaking discoveries of its own researchers and on the development and global distribution of the most diverse collection of genetically unique mouse strains in the world. The Jackson Laboratory is a National Cancer Institute – designated cancer center. Our research covers a broad range of genetic disorders, including cancer, diabetes, neuromuscular and neurodegenerative disorders, autoimmune disorders, and conditions related to reproduction, development and aging. The Laboratory’s mission is to discover the genetic basis for preventing, treating and curing disease, and to enable research and education for the global biomedical community.

Bitesize Bio's Gail Seigel offers some tips on running a low-budget lab.

The GRE isn't a good predictor of graduate school performance or productivity, according to two PLOS One studies.

Bitesize Bio has some advice for scientists ready to leave their current lab behind.

A trio of editors from the Nature family of journals describes what make a peer review a good one.