The Vertebrate Genomes Team seeks an enthusiastic developer to work on comparative genomics for the Ensembl team at the European Bioinformatics Institute (EMBL-EBI), which is located on the Wellcome Trust Genome Campus near Cambridge in the UK.
Ensembl (https://www.ensembl.org/) is one of the most successful large-scale bioinformatics projects and one of the leading projects for genome annotation. Large-scale sequencing projects are now collecting genome sequences from hundreds of new species, and further orders of magnitude will be reached in the next years (for example the Genome 10K project). These data will contribute to improving our knowledge and understanding of the evolutionary history of vertebrate genes and genomes, and the connection between genome evolution and speciation. In light of these new resources, we are looking for an additional member for the team to expand and develop the comparative genomics databases for Ensembl.
The successful candidate will be involved in creating the Ensembl comparative genomics resources as well as in maintaining and developing the production pipeline and the associated Perl API.
Reporting to the Ensembl Comparative Genomics Project Leader, the developer's primary task will be to maintain and develop the whole-genome alignment component of the Ensembl project. This will include working closely with collaborators and keeping up-to-date with scientific research in the area of genome alignments, including aligners (eg Cactus) and file formats (e.g. HAL - Hierarchical Alignment Format). Derived resources that are currently produced, such as GERP and synteny analysis, may also be expanded to new resources of interest to the Ensembl project and community.
In particular, and in addition, to the above, this role will involve:
- Maintaining and developing the Ensembl Comparative Genomics pipelines, databases and API.
- Helping with coordination of the Ensembl comparative genomics release process.
- Supporting the Ensembl Genomes team and other external users in their use of the comparative genomics pipelines.
- Collaborating and coordinating with peers at the UCSC genome browser on the development of the tools and creation of resources.
- Teaching the usage of the Ensembl Compara Perl API at the quarterly PI workshops (http://www.ensembl.info/workshops/)
- Participation in collaborations between Ensembl and research groups/consortia.
- Representing the project and the institute at conferences.
The EBI is part of the European Molocular Biology Laboratory(EMBL) and is Europe's leading provider of information services to biological researchers in academia and industry. EMBL-EBI staff enjoy many benefits including sports facilities, a free shuttle bus to Cambridge and other nearby centres, and an attractive working environment set in 55 acres of parkland. Our salary scales are very competitive.
For further information please visit www.ebi.ac.uk